Hotspot dialogue

　　During the two sessions of the National People’s Congress, Beijing Youth Daily reporter interviewed Chen Hongbin, deputy to the National People’s Congress and director of the Supervision Office of Yancheng No.1 Primary School.

　　Classroom efficiency has been improved after "double reduction"

　　Beiqing Daily: How many years have you worked in Yancheng No.1 Primary School?

　　Chen Hongbin: I was assigned to work in Yancheng No.1 Primary School in 2001. Since 2009, I have served as the director of the comprehensive department of Yancheng Experimental Primary School, the director of the information center of Yancheng No.1 Primary School Education Group, and now I am the director of the supervision office of Yancheng No.1 Primary School.

　　Beiqing Daily: It has been more than a year since the "double reduction" policy was introduced. What is the current academic status of primary school students?

　　Chen Hongbin: It is definitely different from the situation before the "double reduction".

　　First of all, the burden of off-campus training for students is basically gone. Take Yancheng, where I live, as an example. Through the strict control and governance of our education authorities, there are no cultural extracurricular tutoring institutions now. For children, it really lightens the burden. Secondly, the children’s homework burden is also reduced, and the classroom efficiency is higher.

　　It is suggested that social professionals participate.

　　Beiqing Daily: The "double reduction" policy has achieved the goal of reducing the burden and improving the quality. What are the difficulties at present?

　　Chen Hongbin: After the "double reduction", the workload of teachers has increased, and they may spend up to 10 hours in school every day, which reduces the time for teachers to participate in scientific research, teaching and research activities. Why do teachers spend more time at school? Because of the after-school delay service.

　　In order to better meet the diverse after-school service needs of students, the Ministry of Education has made special arrangements for further improving the after-school service of compulsory education for many times, and promoted the after-school service to be further detailed and practical.

　　Our school is also trying to create such an environment. However, after all, there are still insufficient professional personnel, because there are so many teachers who teach music, physical education, beauty, science and technology. So this time I have a suggestion — — Establishing a long-term and effective guarantee mechanism for social professionals to participate in after-school delay service can enrich the content of students’ after-school delay service, and on the other hand, it can reduce the time burden brought by "double reduction" to teachers to some extent.

　　Beiqing Daily: How did your school solve the above problems?

　　Chen Hongbin: On the one hand, we seek some professionals to enter the campus to participate in after-school delayed service through resources from parents and society. However, this is often a feeling, and the liquidity is relatively large, which brings difficulties to the quality assurance of delayed service.

　　Our school is also strengthening teaching and research activities, especially the teaching and research of homework. For example, we have developed some long-distance homework, and the content of homework is not only around grades, but also to increase children’s practical experience, such as adding small experiments in science and technology, which has expanded students’ practical ability.

　　Delayed service after class needs financial support.

　　Beiqing Daily: How do you think to establish a long-term and effective guarantee mechanism?

　　Chen Hongbin: I think it is necessary to establish a financial guarantee mechanism. If the relevant social workers are allowed to participate in the after-school delayed service for a long time, they need financial resources as a guarantee. According to their workload, it is both recognition and respect for them to pay appropriate labor remuneration.

　　In addition, the human security mechanism should also keep up. At present, most university teachers and professionals participate in the delayed service in their personal capacity, and the original unit has no corresponding support mechanism. In order to let them participate in the after-school delay service in primary and secondary schools for a long time, it is necessary for these units, preferably the higher authorities, to introduce relevant systems, recognize and support their work, and include them in the assessment category, so as to establish a long-term guarantee mechanism. Text/reporter Meng Yaxu

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　　The Central Radio and Television General Station has submitted three representative works and their two-dimensional codes as required in the submitted materials of the work "Walking the Village Live to See Poverty Alleviation", the media integration award of the 31st China News Award. In view of the fact that "Walking the Village Live to See Poverty Alleviation" is a large-scale media report, it has successively entered 101 typical poverty alleviation villages in 23 provinces, autonomous regions and municipalities directly under the Central Government, lasted for 100 days, broadcasted 101 games, traveled more than 30,000 kilometers, and used various methods such as graphics, text, live broadcast, short video, and small games to integrate and spread on TV, radio and new media, and published more than 900 articles of various types. The three representative works previously reported can’t fully reflect the scale and the characteristics of integration and innovation of this media action, so the QR code of the main page of "Going to the Village to Live and See Poverty Alleviation" is specially added. Now the complete participating materials will be publicized.

　　According to the "China News Award Selection Method", the works to be recommended will be publicized on the public news website for not less than 5 working days, and the supplementary publicity period of the participating materials of "Going to the Village to Watch Poverty Alleviation" is from June 7 to June 15, 2021. Please inform the department personnel of the publicity content in a timely manner. Departments or individuals can put forward written opinions to the Academic Liaison Department of the Innovation and Development Research Center for the problems existing in the publicity works, and will not accept them after the deadline.

　　Tel: 85057327, 85057328, 85057329, 85057330; E-mail: xsllb@cnr.cn.

　　Central radio and television main station

　　Innovation and development research center

　　June 7, 2021

China News Award Media Convergence Award Recommended Works Table

　　Description of the duration of "Going to the Village Live to See Poverty Alleviation"

　　The large-scale media action of "Going to the Village to Watch Poverty Alleviation", the financial channel launched 101 live broadcasts and broadcast 307 news items, with a total broadcast time of 820 minutes; Voice of the Economy and China Communications Radio broadcast audio reports for 427 minutes; CCTV Financial New Media launched 101 live broadcasts with a total duration of 6,091 minutes.

　　List of creative personnel and editors of "Going to the Village to Watch Poverty Alleviation"

　　Founder (12 people):

　　Peng Jianming, Liang Jianzeng, Chen Yongqing, Yang Chunyang, Dong Chunhu, Ke Chengyun, Ha Xuesheng, Zhang Xiaoli, Luo Min, Liu Yang, Feng Yuting and Tao Haijun.

　　Editor (188 persons):

　　Wei Xingran, Xin Yong, Xue Qian, Li Qing, Siqin, Tang Hesong, Yang Yi, Ma Chao, lin li, huyuan, Tong Ying, Dai Yuling, Xie Lin, Yang Quanlu, Li Sixuan, Zhang Lin, Chen Weihong, Xie Yingying, Meng Zhandong, Chen Haobing, Meng Xiabing, Yi Yang, Yuan Yi, Su Tong, Zhao Yang. He Jiajing, Ning Kun, Zhang Qinsi, Huang Xiaoli, Tianqi Tang, Zhang Luxin, Xiao Rong, Zhang Ning, Wang Yu, Chen Yuyou, Wang Xueqing, Zhang Tingmin, Yang Yiran, Li Yuan, Liu Xiaofan, Yu Xiaoman, Li Tianlu, Li Yiyang, Xiang Bo, Yang Yinyin, Wu Baichen and Zhang Biaohan. Wang Jiankun, Xu Xinyu, Zhang Zheng, Mao Mingyang, Wei Liming, Bu Ride, Army, Jiang Fuhai, Xing Jie, Ning Tao, Liao Wenzheng, Yao Jia, Liu Jun, Meng Xing, Luo Meng, Wu Junhu, Zhang Zhengyu, Zhao Bo, Yang Zheng, Liu Yongbo, Gao Wenpeng, Chen Mingyu, Liu Weiyong, Zhao Xiaowei, Zhang Junyu. Liu Xuening, Zhang Qiuyuan, Xi Shanshan, Li Yu, Zhao Yuxi, Hu Longchao, Song Ruijuan, Gao Lei, Li Gaopeng, Yi Zeke, Yu Dongtao, Guo Jinqiu, Chen Lun, Lu Qun, Liu Xuerong,Wang Yanlin, Zhang Yu, Yu Qianqian, Liu Yile, Tang Liang, Wang Guan, Zhang Bin, Liu Xiaoguang, Ren Fangzhu, Jiang Yao, Xie Huayu, Yang Bo, Tian Fangyu, Xia Qing, Luo Jiaying, Tang Yingzi, Zhang Ziyi, Wang Zhiliang, Man Hengyu, Cui Shiwei, Zhong Huiwei, Liu Ning, Lei Zhangjun, Duan Lei,.

　　(200 persons in total)

　　The specific division of labor between the main creative staff and editors of "Going to the Village Live to See Poverty Alleviation"

　　Chief planner (7 persons): Peng Jianming, Liang Jianzeng, Chen Yongqing, Yang Chunyang, Dong Chunhu, Ke Chengyun and Ha Xuesheng.

　　Producer (1 person): Zhang Xiaoli

　　Chief Directors (18 persons): Luo Min, Feng Yuting, Xin Yong, Liu Yang, Xue Qian, Li Qing, Siqin, Tang Hesong, Yang Jie, Ma Chao, lin li, huyuan, Tong Ying, Tao Haijun, Wei Xingran, Dai Yuling, Xie Lin and Yang Quanlu.

　　Reporter (34 persons): Li Sixuan, Zhang Lin, Chen Weihong, Xie Yingying, Meng Zhandong, Chen Haobing, Meng Xiabing, Jerry Liau, Yuan Yi, Su Tong, Zhao Yuanyuan, Pei Lei, Wang Xiaolin, Qiao Nan, Sheng Hua, Song Hua, Xia Meizi, Bai Yue, Ma Jialun, Zhang Weijie, Wu Nanxin, Wang Wencong and Zhang Xinyue.

　　On-site directors (9 persons): Xiao Rong, Zhang Ning, Wang Yu, Chen Yuyu, Wang Xueqing, Zhang Tingmin, Yang Yiran, Li Yuan and Liu Xiaofan.

　　New media communication (25 people): Yu Xiaoman, Li Tianlu, Li Yiyang, Xiang Bo, Yang Yinyin, Wu Baichen, Zhang Wei Han, Jin Luya, Zhang Yifei, Liu Like, Li Zeping, Wang Xiaoyu, Wang Yihan, Lu Tianxiang, Dai Yuanjun, Ren Mingzhe, Lei Ji, Qu Jida, Xie.

　　Camera (26 people): Wang Jiankun, Xu Xinyu, Zhang Zheng, Mao Mingyang, Wei Liming, Bu Ride, Lu Jun, Jiang Fuhai, Xing Jie, Ning Tao, Liao Wenzheng, Yao Jia, Liu Jun, Meng Xing, Luo Meng, Wu Junhu, Zhang Zhengyu, Zhao Bo, Yang Zheng, Liu Yongbo, Gao Wenpeng, Chen Mingyu, Liu Yongbo.

　　Outreach (47 persons): Wang Xiaoya, Zhang Kaihua, Meng Li, Du Yang, Deng Yan, Dong Yingchun, Yan Yichen, Huang Yiwen, Wu Danhua, Xu Lei, Jia Honglu, Su Qi, Jiang Wenbo, Gu Yandong, Li Yi, Liu Xuening, Zhang Qiuyuan, Xi Shanshan, Li Yu, Zhao Zixi and Hu Longchao.

　　Producers (11 persons): Wang Zhiliang, Man Hengyu, Cui Shiwei, Zhong Huiwei, Liu Ning, Lei Zhangjun, Duan Lei, Hu Fenglong, Li Wensheng, Yu Yun and Jiang Guo.

　　Program coordinator (1 person): Jie Yu

　　Packaging (4 persons): Keke, Shi Miao, Zhu Bocheng and Wang Xiangguo.

　　Live broadcast supervisor (5 persons): Pei Feng, Zhang Han, Lei Zhang, Dong Kexin, Wang Zhe.

　　Director (8 persons): He Lili, Li Duhui, Qu Peng, Chi Cheng, Liu Wei, Chen Liang, Liu Jin and Xu Yun.

　　Technology (4 persons): Chen Xin, Xu Yan, Yang Shaotong, Qi Yi.

　　(200 persons in total)

　　QR code of the main page of "Going to the village to watch poverty alleviation"

　　The main page of "Walking the Village Live to See Poverty Alleviation" adopts the guide mode, and the two caravans in the north and south are continuously updated according to the driving route. Every time I go to a village, the reporter produces a variety of new media products, including: live broadcast, I am the anchor of the village, a cloud view of beautiful countryside in China, a reporter’s Vlog in the village, and a small game: getting rid of poverty and running towards a well-off society, and the interaction of the whole people to praise my hometown. This page integrates a variety of new media products, which is convenient for users to participate in the interaction of the village action more intuitively and praise the poverty-stricken villages they support. Through the main page, you can find the following three masterpieces. See "Go to the main page of < Go to the village to watch poverty alleviation > to find Theory of Three Represents as a process guide".

　　Three representative QR codes

　　Representative work 1 "The reporter goes to the village Vlog｜ | The old village in the Yellow River beach area has become a fish pond, and the village has increased its income by millions! Braised fish sweet and sour fish &hellip; &hellip; Miss CCTV takes you to punch in the N ways of eating Yellow River carp! 》

　　Masterpiece 2, "When the farmer is the anchor, does it miss?" Come on, show it! Rural rap, sonorous Henan opera &hellip; &hellip; Don’t be too stylish! 》

　　Masterpiece 3 "[Tianxia Finance] Going to the Village Live to See Poverty Alleviation and Entering Nangou Village, Ansai District, Yan ‘an City, Shaanxi Province"

　　Representative manuscript of "Going to the Village Live to See Poverty Alleviation"

　　The reporter went to the village Vlog｜ | The old village in the Yellow River beach area became a fish pond, and the village increased its income by millions! Braised fish sweet and sour fish &hellip; &hellip; Miss CCTV takes you to punch in the N ways of eating Yellow River carp!

　　[Video promotion manuscript]

　　The large-scale financial media action sponsored by the Financial Program Center of the Central Radio and Television General Station # Go to the village to watch poverty alleviation # came to Qian’ an community in Fan County, Henan Province. In the past, there were more than 90,000 people living in the Yellow River floodplain in Fanxian County, and they faced the risk of the Yellow River floodplain every flood season. Nowadays, the residents in the beach area have moved in batches, and the local residents have also changed from competing for land and water to nurturing people. Qianfang village has developed a running water fish farming project, raising hundreds of thousands of fish, with an annual income of 1.5 million yuan. In 2019, the per capita disposable income of rural residents in Fan County exceeded 10,000 yuan. In February this year, the "hat" of poor counties was officially removed. Meng Xia Bing, a CCTV financial reporter, takes you to explore the Yellow River carp breeding grounds and punch in the N ways to eat the Yellow River carp!

　　[Short video content and caption]

　　Reporter: This fish looks delicious!

　　Schreiber: This is koi fish. You can’t eat it.

　　Reporter: I made a mistake and started again. We also have edible Yellow River carp next to us. Today, I will introduce you to N ways to eat Yellow River carp.

　　Sound effect: Help!

　　Reporter: It’s just delicious. Come on, have another piece.

　　Subtitles:

　　Explore carp breeding grounds together

　　Venue: Fish Pond in Qianfang Village, Fan County, Henan Province

　　Reporter: Our location is less than two kilometers away from the Yellow River. This is a very typical Yellow River beach area. In the past, more than 90,000 people in Fan County lived in such a Yellow River beach area. However, now they have moved to nearby communities one by one, leading a stable life. After they moved upstairs, they still need some industrial support, one of which is the treasure in the water around me, the Yellow River carp. Let’s catch a fish for everyone to have a look at first. Master, please help us catch a fish. Ok.

　　You can see that this is very exciting! This fish, as you can see, has one characteristic: its scales are golden yellow and its tail is red. We can transport it by this kind of oxygen-filled bag. Such a fish, more than two kilograms of fish can be sent home. At present, its transportation radius is only over 300 kilometers. In the future, by adding dry ice and other technical means, the transportation range of such bags will reach over 1,000 kilometers, and many cities across the country can eat such Yellow River carp.

　　Subtitles:

　　Qianfang Village invested 1.5 million yuan to develop running water fish farming project.

　　This 50-acre fish pond has raised hundreds of thousands of fish and earned 1.5 million yuan a year.

　　Subtitles:

　　In addition to aquaculture, Fanxian also cultivates organic fruits and vegetables.

　　Mushroom cultivation and lotus root cultivation and other industries.

　　Subtitles:

　　In 2019, the per capita disposable income of rural residents in Fanxian County exceeded 10,000 yuan.

　　In February this year, the "hat" of poor counties was officially removed.

　　When our farmers are anchors, do they miss? Come on, show it!

　　Rural rap, sonorous Henan opera &hellip; &hellip; Don’t be too stylish!

　　[Video promotion manuscript]

　　"Once saline-alkali waterlogging, now grain and oil are high; It used to be windy and dusty, but now paulownia is towering. " Two villagers from Zhangzhuang Village, Lankao, Henan Province, walked into the caravan studio and became village anchors! Singing new changes in the countryside with rural rap! ?

　　On July 27 th, the large-scale media-melting action "Go to the village to watch poverty alleviation" brought a caravan with 5G new media mobile cloud production and broadcasting system into Zhangzhuang Village, Lankao, Henan Province! Poke video &darr; Look at the style of the village anchors!

　　[Short video content and caption]

　　Subtitles:

　　Our farmers miss when they are anchors?

　　Come on! Show!

　　Simultaneous subtitles:

　　Female: I used to be waterlogged with salt and alkali.

　　Men and women: Welcome to CCTV Finance Live Broadcasting to watch the news from the anchor of poverty-stricken farmers.

　　Name bar:

　　Zhang Xiangge, a villager in Zhangzhuang, Lankao, Henan Province

　　Bian Tieshan, a villager from Zhangzhuang, Lankao, Henan

　　Simultaneous subtitles:

　　M: Yesterday, I gave it to the village committee, Mengli Zhangzhuang Art Troupe.

　　Performed a Henan Opera chorus "I like to see the new changes in Lankao"

　　W: I also saw the great changes in Lankao.

　　Let’s see who can tell us more about Lankao.

　　Then I’ll go first

　　Once waterlogged and saline-alkali, now grain and oil are abundant, once windy and dusty, now paulownia is towering.

　　M: There’s more.

　　Efficient and intensive three-dimensional planting for irrigation and fertile fields in water conservancy construction

　　Large-scale breeding of pigs, fat cows and strong paulownia is famous for processing musical instruments.

　　Woman: Haha, you make me want to sing a few words.

　　The villagers rolled up their sleeves and worked hard to get rid of poverty and become rich and well-off

　　E-baby hi. Yeah, e-baby hi.

　　Subtitles:

　　Don’t go! And eggs!

　　The caravan entered Zhangzhuang Village, Lankao, Henan Province.

　　Villagers act as village anchors.

　　Go live to see poverty alleviation and walk into Nangou Village, Ansai, Shaanxi Province.

　　Title 1:

　　Ansai, Shaanxi Province: Hundreds of drums resound through Tianshan Village, giving it a new look.

　　Title 2:

　　Ansai, Shaanxi: It is more prosperous to plant apples with a waist drum and a purse drum.

　　Lead: Continue to pay attention to the large-scale media-melting action of "Walking the Village Live to See Poverty Alleviation". Today, our caravan came to Nangou Village, Ansai District, Yan ‘an City, Shaanxi Province, which is also the 101st village we entered. With the unique climatic conditions, the planting area of mountain apples in Nangou Village has reached 3 mu per capita and 10 mu per household. On this basis, Nangou Village has revitalized 22,000 mu of idle land through the introduction of enterprises, and turned the poor mountain village into an eco-agricultural demonstration park integrating recreation and modern agriculture. Let’s connect with the reporter Jerry Liau who is in front, and ask her to tell us something about Nangou Village.

　　In the same period: Jerry Liau reporter

　　The drums you are hearing now come from 101 Ansai waist drummers, which also means that we have come to the 101st stop, Nangou Village, Ansai District, Shaanxi Province. The local farmers performed waist drum performances for us, and the powerful drums echoed on the loess high slope, and the stories that happened to them were even more exciting.

　　In the same period: Jerry Liau reporter

　　The waist drum performance is magnificent, and the production needs to be carefully crafted. Under the leadership of the old master, after 13 processes of manual waist drum, it finally made a crisp sound, and it is our out-and-out farmers who inherit this ancient craft. Bright folk culture makes the farmers on the yellow land versatile. Going out is a waist drum team, sitting down and becoming craftsmen. These poverty alleviation factories, which can promote the employment of the whole village, are blooming everywhere in the small farmyard. There is no roar of machines here, instead, it is the northern Shaanxi folk song Xintianyou, and the woman’s paper is upstream.

　　During the same period: Ansai folk paper-cut artists

　　The master teaches paper-cutting for free. When the order comes around, you can earn money by sitting on the kang. Paper-cutting is valuable, culture is priceless, paper-cutting is valuable and culture is priceless.

　　In the same period: Jerry Liau reporter

　　The waist drum boomed, the paper-cut was red, and the red apples were picked, and the days were even more prosperous. These fresh fruits picked this morning will soon be boxed and sent to consumers who adopt apple trees. The unique climatic conditions make the planting scale of mountain apples here reach 3 mu per capita and 10 mu per household. 3,000 mu of apple orchard and 20,000 mu of idle land have been revitalized. Nangou Village has built an eco-agricultural demonstration zone by introducing enterprises. Nowadays, every household is a shareholder and every family can get dividends. The mountainous area becomes a scenic spot, and the mountain becomes a work. Up to now, the per capita income of Nangou Village has exceeded 15,000 yuan.

　　During the same period: apple growers

　　When it comes to income, it will bloom, and 3,000 cards will be scored every month. Water and fertilization will be mechanized, and dividends will be indispensable at the end of the year. The mountain orchard has a good scenery, and the children in the city run here. Come to Nangou to recognize trees, and your site is up to you.

　　In the same period: Jerry Liau reporter

　　Apples have been sold by the catty in the past, and now they are sold by the individual and the tree. In Nangou Village, the proportion of agricultural industry and rural tourism in villagers’ income reached 61% and 31% respectively. It has realized the deep integration of culture, agriculture and tourism.

　　On this five-meter scroll, the farmer painter recorded the life changes in his hometown in recent years. Colorful flowers blossomed on the yellow land, and tourists flocked to the small mountain village. The newly-built small building had white walls and tiles, and the sweet fruit was praised by everyone. The changes that took place in Nangou are just a microcosm of Ansai District’s efforts to get rid of poverty. Ansai has helped the masses to achieve industrial poverty alleviation through mountain apples, greenhouse vegetables and special farming. At the same time, it has revitalized five cultural business cards, namely waist drum, paper-cutting, folk songs, peasant paintings and folk art, and realized cultural enrichment. It is estimated that by the end of this year, the per capita disposable income of farmers in the whole region will reach 13,500 yuan.

　　In the same period: Jerry Liau reporter

　　The story here is still going on. Let’s send the loudest blessing to the 101 villages that have gone through the live broadcast of poverty alleviation through the 101 Ansai waist drums on the spot!

　　Enter the main page of "Going to the Village to Watch Poverty Alleviation" to find Theory of Three Represents as a process guide.

　　First, scan into the main page of "Going to the Village to Watch Poverty Alleviation"

　　Second, find three representative work process guidelines

　　Representative work 1 "The reporter goes to the village Vlog｜ | The old village in the Yellow River beach area has become a fish pond, and the village has increased its income by millions! Braised fish sweet and sour fish &hellip; &hellip; Miss CCTV takes you to punch in the N ways of eating Yellow River carp! 》

　　1. Click the locate button.

　　2. Click the Henan option

　　3. Find Qian ‘an Community in Henan, and click to locate it. Or directly find Qian ‘an Community in Henan on H5 page.

　　4. Click on the "wooden sign" expansion option, and select "reporter goes to the village Vlog" to watch the masterpiece "reporter goes to the village vlog | the old village in the Yellow River beach area becomes a fish pond, and the whole village has increased its income by millions! Braised fish sweet and sour fish &hellip; &hellip; Miss CCTV takes you to punch in the N ways of eating Yellow River carp! 》

　　Masterpiece 2, "When the farmer is the anchor, does it miss?" Come on, show it! Rural rap, sonorous Henan opera &hellip; &hellip; Don’t be too stylish! 》

　　1. Click the locate button.

　　2. Click the Henan option

　　3. Find Zhangzhuang Village in Henan Province and click to locate it. Or directly find Zhangzhuang village in Henan province in H5 page.

　　4. Click on the option of’ re expansion, and select "I am the village anchor" to watch the second masterpiece "My farmers are the anchors, but I miss it? Come on, show it! Rural rap, sonorous Henan opera &hellip; &hellip; Don’t be too stylish! 》

　　Masterpiece 3 "[Tianxia Finance] Going to the Village Live to See Poverty Alleviation and Entering Nangou Village, Ansai District, Yan ‘an City, Shaanxi Province"

　　1. Click the locate button.

　　2. Click Shaanxi option.

　　3. Find Nangou Village in Shaanxi and click to locate it. Or find Nangou Village in Shaanxi directly in H5 page.

　　4. Click on the option of "expanding" and select "Live" to watch the masterpiece 3 "[Tianxia Finance] Going to the Village Live to See Poverty Alleviation and Entering Nangou Village, Ansai District, Yan ‘an City, Shaanxi Province"

　　"Three months is 8 cm tall!"

　　In 2017, a propaganda by Green Cool High official website made Xiao Shen (a pseudonym) who wanted to grow taller move. He spent 920 yuan to buy three boxes.

　　Xiao Shen, 21 years old, a college student in Chengdu, is 165cm tall. In the two years after he first bought diet pills, he kept buying a variety of health care products, with a total cost of 60 thousand yuan.

　　"In the past two years, I have been taking medicine on time, doing push-ups every day, not smoking or drinking, not eating peppers or coriander, and doing it in full accordance with the words of the development guidance teacher." Xiao Shen said that after eating for two years, he found that his height did not change at all, and he did not grow taller by 1 cm!

　　On July 8, a medical expert on growth and development said in an interview with Chengdu Business Daily-Red Star News that the epiphyseal line of adults is closed, and nothing can grow taller. In the adult world, there is no medicine to increase height.

　　Be bent on growing taller.

　　I took 60,000 yuan of high-altitude medicine for two years.

　　In 2017, Xiao Shen was 19 years old and just entered the university. He was only 165cm tall and wanted to grow taller. He searched Baidu for "ways to increase height" and found a "green, cool and tall" official website. A slogan on the webpage made him quite tempted.

　　"It is official certification and can grow to 8 cm in three months." Xiao Shen said that he wanted to grow to 170cm, and he left his contact information in the dialog box.

　　Soon, the salesperson of Lvkugao added his WeChat, and he spent 920 yuan to buy three boxes of Lvkugao, which lasted for three months, just one course of treatment. In order not to affect the drug effect, the development guidance teacher explained that he should take the medicine within half an hour after meals every day, and do 50 squats and 50 push-ups every day.

　　"It’s just a matter of taking medicine. You can’t smoke or drink, and you can’t eat Chili or coriander." Xiao Shen said that he came from Jiangxi and fell in love with spicy food when he came to Chengdu, but in order to grow taller, he put up with it and did it one by one. A week later, the salesperson asked him if he had any reaction after taking the medicine, such as fever on the soles of his feet and fever on his knees.

　　"Yes, there is. There is a cramp in the knee, like stretching, and there is a fever." Xiao Shen said that he was very happy. Under the sales promotion, he spent another 3,200 yuan to buy stem cell activin.

　　One morning after taking the medicine for a month, he measured his height with a tape measure.

　　"At that time, it was 0.8 cm long." Xiao Shen said that from then on, he was convinced of the salesperson’s words, although it was later confirmed that this 0.8 cm was just a miscalculation or a normal gap in height in the morning and evening. "Later, I asked them why it didn’t last long. They answered me that because I have toxins in my body, I need to detoxify."

　　"Detoxification needs to buy drugs, and protein’s cooperation is better", one cover after another. In the next two years, Xiao Shen transferred 60,000 yuan to these so-called "development instructors" and bought more than a dozen health care products by mail. He followed the instructions, took medicine on time, and took at most a dozen pills at a time. In order to avoid being discovered by his classmates, he took them secretly.

　　Later, the salesmen changed frequently, and everyone made him buy medicine in a different way, but after taking the medicine, his height remained motionless, and he began to have some doubts.

　　"I asked them why they were not tall. They said that the best medicine was given to you. You are in a special situation and there is really no way to make me look down." Xiao Shen said that the consensus of many instructors made him feel that his physique was really different from ordinary people. He still hopes that these height-increasing drugs are real and can help him grow taller.

　　Most of the heightening drugs are health care products.

　　Company: It sells calcium tablets.

　　In October last year, Xiao Shen consulted a lawyer, and finally he was completely sure that what the salesman said was just a set of words. "I was completely cheated. What is depressing is that I really dare not put parsley in these two years." On July 7, the reporter saw Xiao Shen near a university in Shuangliu District. He was a strong man with handsome features and a spirit.

　　I was worried that my classmates would find out that he used two backpacks to pack the heightening drugs tightly, and dumped the bag underground, and it fell all over the floor. The reporter counted a total of more than 30 bottles with more than a dozen varieties, some of which were empty, and some were still left.

　　The reporter looked at the ingredients of "drugs", such as the ingredients of calcium tablets for bones and muscles are edible corn starch, maltodextrin, whole milk powder, etc. The ingredients of small molecular collagen peptide solid beverage are collagen, marine fish oligopeptide powder, etc. Beibei Gaole ingredients are dried tangerine peel, malt, calcium gluconate, vitamins, etc. Most of them belong to health care products, and their function is to enhance immunity. The WeChat transfer record displayed by Xiao Shen shows that on November 24, 2017 alone, he transferred a total of 32,000 yuan to the teacher named "Teacher Bai, the development guidance teacher".

　　"At that time, she told me not to transfer more at once, but to transfer separately. Every time they said that it was the last payment and there was no need for any fees, and then they repeated these words." Xiao Shen said that in October last year, he stopped buying and taking medicine and began to collect evidence to find a lawyer to sue. But the funny thing is that up to now, Xiao Shen doesn’t know which company the person who sells health care products to him belongs to.

　　On July 8, according to more than a dozen calls provided by Xiao Shen, the reporter dialed a landline, and confirmed to the reporter that they were Guangzhou Jianchang Biotechnology Development Co., Ltd., and the name of the merchant receiving Xiao Shen WeChat also indicated that it was this company, and the national industrial and commercial information inquiry, this company has been cancelled.

　　"Xiao Shen’s medicines are all sold to him by us, and his situation is really special." The staff member said. Subsequently, Mr. Qiu, who claimed to be the head of the company’s growth and development, responded to the reporter that at that time, the company did a genetic test for Xiao Shen, which showed that his bone nutrition was not enough and he needed to supplement calcium tablets.

　　"At that time, we told him that this is the same as calcium tablets. His bones feel sour and need to be supplemented with calcium tablets. What we sell is calcium tablets, and the instructor also said that he has grown three or four centimeters, but he has not grown behind, which has not achieved the expected effect." Mr. Qiu said that if Xiao Shen wants a refund, he can negotiate.

　　Expert:

　　It doesn’t matter what height-increasing drugs adults take.

　　For adults with closed epiphyseal lines, are there any effective height-increasing drugs in the world?

　　Luo Lei, director and associate professor of the Department of Orthopedics and Trauma of the Affiliated Hospital of Chengdu Institute of Physical Education, said that when people become adults, the epiphyseal line is closed, and their height stops growing. The age when girls close the epiphyseal line is 17 to 18 years old, and boys are slightly later, ranging from 18 to 20 years old. He said: "In the world of adults, there is no height-increasing drug."

　　"Anyone who has studied pharmacology knows that drugs have little effect on height." Luo Lei said that a person’s height is mainly related to congenital inheritance, and the acquired nutritional status and exercise degree can also affect his height. In real life, we can see that some children are much taller than their parents, and some can grow taller at the age of 20. "But this probability is very low."

　　Xiong Youhua, dean of Chengdu Southwest Children’s Hospital, also said: "The epiphyseal line has been closed and the height no longer grows."

　　"Adults will not grow up no matter what they eat, and the health care products sold outside are useless." Xiong Youhua said that height is 70% determined by heredity and 30% by acquired factors, including exercise, nutritional status, sleep and so on. "If a child is taller than his parents, acquired factors play a big role."

　　Chengdu Business Daily-Red Star Journalist Zhong Meilan

　　Since September 2021, China’s regulatory policy on virtual currency has been upgraded in an all-round way, and various provinces, cities and autonomous regions have successively carried out relevant special rectification actions. On January 26th, the Inner Mongolia Development and Reform Commission issued a notice, deciding to implement the differential electricity price for the virtual currency "mining" project and the "eliminated" enterprise electricity price, with the price increase standard of 1 yuan per kWh (per kWh).

　　On December 3, 2021, Hainan Provincial Development and Reform Commission took the lead in issuing a notice, deciding to classify virtual currency "mining" activities as obsolete industries, and implement differential electricity prices, with the price increase standard of 0.8 yuan per kWh (kWh).

　　A bitcoin investor told The Paper that the policy of differential electricity price is not to allow bitcoin mining, and the policy of cracking down on bitcoin mining is still going on.

　　"The main cost of digging bitcoin is electricity. When bitcoin mining was not cracked down before, the approximate cost of large mines was more than 30 cents for thermal power in winter and cheaper for hydropower in summer. And if the electricity bill increases by 0.8-1 yuan, then digging bitcoin is bound to be a serious loss. " The investor said.

　　Sun Yulin, a senior researcher at Ou Ke Cloud Chain Research Institute, also told The Paper that the implementation of differential electricity prices in Inner Mongolia and Hainan will obviously increase the cost of bitcoin mining. According to the master data on the Okeyun chain, according to the current differential electricity price, the annual electricity fee for each bitcoin mining machine is about 10,000 yuan, and the mining time is about 2 years. After the differential electricity price is implemented, the return time is far away and the electricity cost will increase by about 4 times. Currency price of mainstream mining institutions (data source: f2pool)

　　Take the ant miner S19 as an example, its rated computing power is 95TH/s and its power consumption is 3250w. On January 22nd, based on the electricity fee of 0.1 USD/kWh (i.e. about 0.6 yuan/kWh), f2pool calculated that the pure electricity fee cost (i.e. the shutdown price calculated by f2pool) of this type of mining machine for "mining" a bitcoin was about 17,590 USD. If the electricity fee is increased in 1 yuan, it will be about 2.7 times of the original price, and the pure electricity cost for each bitcoin dug by Ant Mining Machine S19 will also be increased to about 46,907 dollars. At present, the price of Bitcoin is about 35,000-36,000 US dollars, which is far lower than the pure electricity cost of Bitcoin "mining".

　　"Now Bitcoin &lsquo; Mining &rsquo; If you can make a profit, you can either build a mine overseas, or put a few mining machines at home to steal and make money. " The above investors said.

　　Location introduction:

　　In your microsoft account: Log in to your microsoft account on another device to find your recovery key. If other users have accounts on the device, you can ask them to log in to their Microsoft account to see if they have a key.

　　In the saved printout: Your recovery key may be in the printout saved when BitLocker was activated. Look for important files related to your computer.

　　On the USB flash drive: Insert the USB flash drive into the locked PC and follow the instructions. If you have saved the key as a text file on the USB drive, use another computer to read the text file.

　　In an Azure Active Directory account: If your device used a work or school email account to log in to an organization, your recovery key may be stored in the AZURE AD account of the organization associated with your device. You may have direct access to it, or you may need to contact the system administrator to access the recovery key.

　　Owned by your system administrator: If your device is connected to a domain (usually a work or school device), please ask the system administrator for the recovery key.

　　View method:

　　Method 1:

　　Open this pc. At this time, we can see that disk F is encrypted. Double-click it to pop up a dialog box for entering the password. After entering the password, click Unlock in the lower right corner, then right-click the unlocked disk and select Manage BitLocker】； in the pop-up dialog box.

　　After entering the encryption page of BitLocker drive, select 【 Backup Recovery Key 】, and then you can choose the way to save the password, such as 【 Save to File 】, set the save path and click 【 Save 】, then open the corresponding save path in the computer to find the file of BitLocker recovery key.

　　Method 2:

　　1. You don’t need to remember the key itself to save the key in Microsoft account, but you can get the recovery key by logging in to Microsoft account (htt://account.microsoft.com/devices/recoverykey). The recovery key consists of 8 6-digit strings with 48 bits in total, and each key has a corresponding key ID corresponding to the corresponding device name and drive name. If you forget your Microsoft account, you can’t recover it.

　　2. Save the recovery key as a text file, which can be flexibly backed up to any location with multiple backups. Open it with notepad of another computer to verify whether the recovery key is correct. First, compare the identifier with the identifier value displayed on the computer, and if it matches, use the key to unlock the encrypted drive.

Original Wuyuan Li Na and other SIFIC infection horizons　

Author: Wu Yuan Li Na Jin Wenting Ma Yuyan

Review: Hu Bijie and Pan Jue

First, a brief introduction to medical history

Male, 63 years old, from Shanghai, was admitted to the Infectious Diseases Department of Zhongshan Hospital for the second time on November 23, 2022.

Chief complaint: indwelling catheterization with repeated urine color turbidity for 2 months and then 8 days.

Current medical history:

On September 19, 2022, I went to a hospital in Shanghai for fatigue, anorexia and dysuria. WBC 10.12×10 9/L, N 87.6%, Hb 53g/L, hsCRP 135.22mg/L, ESR 62mm/H, albumin 30.1g/L, Scr 589μmol/L, K 2 were examined. Urine routine: WBC 3892/ul, occult blood 3+/RBC 5579/ul, protein 2+; Chest CT: bilateral pleural effusion, partial atelectasis of lower lobe of both lungs; Abdominal pelvic CT: Bilateral middle and upper ureteral dilatation and renal pelvis and calyceal dilatation, the patch in the right part of calyceal is slightly high density, the bladder wall is thickened, there is a little flocculent blur around the left renal fat sac and ileocecal part, and there is a little effusion in the pelvic cavity. A large amount of turbid urine was drained by indwelling catheter. Urine culture showed that Klebsiella pneumoniae was positive. Considering urinary tract infection, acute kidney injury, hypokalemia and severe anemia, patients were given symptomatic support treatment such as anti-infection, bladder irrigation, antioxidation, potassium supplementation and blood transfusion. The symptoms of patients improved and the urine was slightly clarified. 10-18 Review urine routine: WBC3+, RBC3+, protein 1+, SCR 263 μ mol/L.

I was admitted to our department on October 19, 2022. Blood routine: WBC 5.08X10 9/L, N 66.1%, inflammatory markers: ESR 19mm/H, hsCRP 52.3mg/L, PCT 0.52ng/ml, Scr 257μmol/L, and urine routine: WBC 28493/μ. Urinary color Doppler ultrasound: hydronephrosis, bilateral ureteral dilatation, bladder wall thickening significantly; Abdominal pelvic CT: hydronephrosis of both renal pelvis and ureter, thickening of ureter wall (inflammatory change), inflammatory change of bladder and ureter may be large, the volume of both kidneys increases and the substance is thin. Meropenem 1g q12h is given for empirical anti-infection. Urology consultation considers the acute stage of infection, so it is not suitable to put double J tubes. If necessary, pyelostomy can be done, but it does not improve renal function much. Bladder irrigation is recommended. 10-20 middle-stage urine culture (sampling on October 19): Klebsiella pneumoniae was positive; 10-22 urine culture drug sensitivity: Carbapenem-resistant Klebsiella pneumoniae (CRKP), adjusted to ceftazidime and abamectin 2.5g q12h for anti-infection, and daily bladder irrigation. After treatment, the urine color of the patients gradually became clear, and the urine white blood cell and bacterial count gradually decreased during follow-up. The urine bacterial culture was negative on November 1 and November 4. Check the urine routine on November 09: WBC 28/uL, RBC 4/uL, urine protein+,bacterial count 29/UL;Blood WBC 7.64×10 9/L, N 76.5%, hs-CRP 0.4mg/L, ESR 25mm/H, PCT 0.18ng/mL, Scr 175μmol/L, which were significantly improved compared with those at admission. Stop ceftazidime and abamectin on November 11 and be discharged.

On November 15, 2022, the patient appeared turbid urine again, and there was no fever and other discomfort. On November 23, he was admitted to the hospital for a second diagnosis and treatment.

Past history: In September, 1991, T12-L1 comminuted fracture was treated with internal fixation. After operation, the catheter was retained for half a year due to urinary incontinence, and then the catheter was removed after urination. There was no urinary tract infection during this period. Diabetes for 16 years, insulin therapy, blood sugar control can be; Hypertension for 5 years, oral amlodipine to reduce blood pressure, blood pressure control can be.

Second, the admission examination (admitted on November 23, 2022)

[physical examination]

T: 36.2℃ P: 90 times/min R: 20 times/min BP: 176/105 mmHg.

Stay in bed, feel refreshed and calm, lose weight, and muscle atrophy of lower limbs; Breathing sounds in both lungs are thick, and dry and wet rales are not heard; The rhythm of the heart is regular, the abdomen is soft, without tenderness and rebound pain, without mass, without percussion pain in both kidneys, without tenderness at ureter point and rib and waist point, and the lower abdomen does not touch the enlarged bladder. During indwelling catheterization, the urine in the urine collection bag is turbid and more white flocs are deposited. Limbs are not swollen.

[Laboratory examination]

Blood routine: WBC 7.85×10 9/L, N 81.3%, HB 121g/L, PLT 170×10 9/L.

Urine routine: WBC 2775/μ l; RBC 2/μl, bacterial count: 39879/μl, nitrite positive, leukocyte esterase+++.

Inflammation markers: hs-CRP 17.9mg/L, ESR 68mm/H, PCT 0.12ng/mL.

Biochemistry: ALT/AST 23/21U/L, Alb 47g/L, Scr 199μmol/L, eGFR 30ml/min/1.73m2, na/k 140/5.5mmol/l.

Third, clinical analysis

Characteristics of medical history: middle-aged and elderly male, indwelling catheter, with repeated urinary turbidity and abnormal urine routine. Urine culture showed CRKP one month ago, and it improved after ceftazidime-ababactam treatment, but urine turbidity reappeared three days after drug withdrawal, blood inflammatory index increased, urinary leukocyte and bacterial count increased significantly, and the diagnosis of urinary tract infection was clear. The reasons for short-term recurrence after antibacterial drug treatment improved were considered:

Recurrence of CRKP infection: The patient has been indwelling catheter for 2 months, and there may be biofilm formation of catheter and abnormal urinary tract structure, which makes it difficult to completely eliminate the infection and relapse after stopping taking the drug. Therefore, urine culture and drug sensitivity test can be improved.

New infection: the patient has high risk factors of recurrent urinary tract infection, and the pathogen may be different each time. The patient’s previous CRKP infection treatment was effective, and the possibility of new pathogen infection should be considered in the short term, until the urine culture is perfect and clear.

Multiple infections: patients with abnormal urinary tract structure, indwelling catheter and other risk factors can not be removed, so it is necessary to be alert to the possibility of multiple pathogens including fungi combined with infection, repeat the cultivation of urine bacteria, mycoplasma, fungi and mycobacteria, and improve urine mNGS to help clarify the infected pathogens.

Four, further examination, diagnosis and treatment process and treatment response

On November 23, 2022, the middle urine smear was used to find bacteria: moderate amount of G- bacilli, and continued ceftazidime and abamectin 2.5g q12h ivgtt for anti-infection and bladder irrigation.

On November 26, 2022, the bacterial drug sensitivity of the middle-stage urine culture (sampling on November 23) was CRKP, ≥ 100,000 /ml, and urine mNGS: a large number of Klebsiella pneumoniae (species strict sequence number: 406,866) was detected.

On November 29, 2022, the abdominal and pelvic CT was reexamined: bilateral dilated hydronephrosis accompanied with inflammatory changes of ureter, and the parenchyma of both kidneys was thin, and the inflammatory changes of cystitis might be larger, similar to that of 22-10-20 slices.

November 30, 2022 (sampling on November 29): Enterococcus faecalis was positive. On December 2, according to the drug sensitivity, fosfomycin 3g qod was added orally, and ceftazidime and abamectin were suspended.

Repeated urine cultures on March, April and June, December, 2022: Enterococcus faecalis was positive and CRKP was negative.

On December 8, 2022, the urine WBC was 38738/μ L, and the bacterial count was 43285/μ L; Urine culture: CRKP positive, Enterococcus faecalis negative.

Phage therapy was carried out from the afternoon of December August, 2022: Phage cocktail (composed of 5 strains of Klebsiella pneumoniae phages A103KP172, A106KP176, A121KP192, A49KP106 and A58KP118, 5mL each), injected with 225mL physiological saline (according to the estimated bladder volume), and the total volume was 250mL, and then the catheter was clamped.

Urine routine on the third day of phage treatment on December 11, 2022: white blood cell count: 235/uL, bacterial count: 722/uL；; Urine bacterial culture was negative.

Urine routine on the 5th day of phage therapy on December 13th, 2022: white blood cell count: 279/uL, bacterial count: 92/ul; Urine bacterial culture was negative; Blood WBC 6.35X109/L, N 70%, hs-CRP 0.9mg/L, ESR 26mm/H, and inflammatory index decreased compared with before; Re-examination of urinary color ultrasound showed that bilateral renal pelvis separation and upper ureteral dilatation were better than before (10-20), and the thickness of bladder wall was reduced (12-25mm→13mm).

He was discharged from hospital on December 14, 2022 for follow-up.

V. Final diagnosis and diagnosis basis

Final diagnosis:

Complex urinary tract infection (CRKP, Enterococcus faecalis)

Neurogenic bladder, hydronephrosis and hydroureter (indwelling catheter)

Renal insufficiency

Diagnostic basis:

The patient is a middle-aged and elderly male with neurogenic bladder caused by paraplegia, indwelling catheter, turbid urine with flocs, increased CRP and PCT, significantly increased WBC and bacterial count in urine, repeated CRKP positive in urine culture, positive in enterococcus faecalis, abdominal basin CT: hydronephrosis of renal pelvis and ureter, anti-infection, normal inflammatory markers and urine routine after phage treatment, clear urine and negative urine culture, so complicated urinary tract infection.

The patient suffered from anorexia and dysuria, and the serum creatinine increased obviously. Abdominal CT showed that both kidneys were enlarged, the cortex was thin, and bilateral urinary tract was hydronephrosis. After active treatment such as controlling infection and improving renal function, the serum creatinine decreased, so the diagnosis of renal insufficiency was clear.

Six, experience and experience

Phage is a targeted sterilization virus in nature and a sterilization star in the "pre-antibiotic era". Phage therapy has a history of more than 100 years, but the discovery and application of broad-spectrum antibiotics have gradually marginalized it. With the increasingly serious problem of bacterial drug resistance, phages have once again received attention and become the most promising supplement and alternative therapy for treating superbugs. The clinical application of phage in China is relatively late, but it has developed rapidly in recent years. In 2017, the Shanghai Institute of Phage and Drug Resistance was established, with Professor Hu Bijie as an academic member. Since 2018, the institute has carried out the first clinical trial of phage therapy in China. At present, it has treated nearly 100 patients with drug-resistant bacterial infections from all over the country and accumulated rich clinical experience in phage therapy, which is a leading position in the field of clinical phage therapy in China.

Phage has many advantages, such as host bacteria dependence, targeted specific sterilization, no infection to eukaryotic cells (little influence on normal flora), no influence on bacterial drug resistance, synergy with antibacterial drugs, penetration of biofilm and so on. The cure rate of acute bacterial infection is high, and the therapeutic effect of chronic bacterial infection is no less than that of antibacterial drugs, and the safety of phage treatment is also extremely high. A systematic retrospective study showed that the vast majority of patients who received phage therapy had no or only slight adverse reactions, 86.7% patients’ clinical symptoms improved, and 78.8% patients achieved the eradication of pathogenic bacteria. Our clinical trials also show that more than 70% of patients have achieved good therapeutic effects, and there are no obvious cases of adverse reactions. This patient was repeatedly infected with Klebsiella pneumoniae due to long-term paraplegia, abnormal urinary tract structure, indwelling catheter and other factors. The diagnosis of complicated urinary tract infection was unquestionable, and the choice of antibacterial drugs was limited due to multi-drug resistance and renal insufficiency. Phage therapy is very suitable.

The disadvantages of phage therapy include narrow host spectrum, individualized plan (it is difficult to treat empirically), no unified standard for the best treatment decision, and rapid tolerance. Phage cocktails, combined antibacterial drugs and multiple treatments are usually used in clinic to improve the curative effect. At present, the targeted pathogens of phage therapy in our team mainly include: multi-drug resistant Gram-negative bacteria (Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecalis); Covering respiratory system, urinary system, abdominal cavity, bones and joints, skin and soft tissue and other infected sites; Treatment depends on the site of infection, and intravenous application of phage is still being explored. In this case, the patient didn’t have percutaneous nephrostomy because of the little clinical benefit, so he was treated by transurethral bladder perfusion, and the phage could not cover the whole urinary tract evenly. Although the pathogen turned negative in a short period of time and was well tolerated, its long-term curative effect may not be good, and it needs repeated phage treatment.

Phage therapy has huge clinical demand and broad market. In recent years, our team has focused on the clinical application (treatment and prevention and control of nosocomial infection) and basic research of phage therapy, with a view to becoming a powerful weapon to curb drug-resistant bacteria in the future.

references

[1] Uyttebroek S, Chen B, Onsea J, Ruythooren F, Debaveye Y, Devolder D, Spriet I, Depypere M, Wagemans J, Lavigne R, Pirnay JP, Merabishvili M, De Munter P, Peetermans WE, Dupont L, Van Gerven L, Metsemakers WJ. Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review. Lancet Infect Dis. 2022 Aug; 22(8):e208-e220.

[2] Chegini Z, Khoshbayan A, Taati Moghadam M, Farahani I, Jazireian P, Shariati A. Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review. Ann Clin Microbiol Antimicrob. 2020 Sep 30; 19(1):45.

[3] Lusiak-Szelachowska M, Weber-Dabrowska B, Gorski A. Bacteriophages and Lysins in Biofilm Control[J]. Virol Sin, 2020,35(2):125-133.

Every Monday night

The Department of Infectious Diseases of Zhongshan Hospital affiliated to Fudan University in Shanghai will be with you!

Photo: Xiaoxiao

Original title: "Detective Case: The Nemesis of Super Bacteria is Coming"

Read the original text

On April 24, Shandong Province pressed the countdown switch for the candidates in the 2020 provincial examination, and Shandong Province made an announcement! As the first province to issue a provincial examination announcement, many students are concerned about what changes have taken place between this year’s provincial examination announcement and previous years. How to prepare as a test preparation party?

The teaching and research group of hornbill public examination made a professional interpretation of the announcement of Shandong provincial examination.

First, from the comparison of data in previous years, we can see the trend of this year’s provincial examination.

Compared with the data in recent years, the total number of applicants has risen sharply for the first time, increasing by 141% according to last year.

Among them, Jining, Linyi, Heze, Yantai and Jinan all recruited more than 600 students.

Weihai, Rizhao, Zibo, Jinan and Yantai increased by more than 3 times.

Among the recruitment regions or institutions in the province, there are 555 recruitment positions in Jining, with 785 people, accounting for 10.7%, ranking first.

Compared with previous years, the position of "high school and technical secondary school" was cancelled, and the minimum academic qualification limit was "junior college"

The five departments with the largest number of candidates come from four regions/institutions, and Yantai has two seats.

Second, in-depth interpretation of the provincial examination announcement, accurately positioning the preparation direction

First, highlight political standards.

Adhere to the guidance of the Supreme Leader’s Socialism with Chinese characteristics Thought in the new era, implement the Party’s organizational line in the new era, adhere to the principle of party management of cadres, adhere to both ability and political integrity, and put morality first, and put political requirements throughout the whole recruitment process. The content of the exam focuses on the ability to solve problems under the guidance of the supreme leader Socialism with Chinese characteristics Thought in the new era; The inspection session focuses on understanding the candidates’ political beliefs, political positions, political awareness and political performance. By checking the source, we will ensure that the newly recruited civil servants have excellent political quality and good moral conduct.

Interpretation of teaching and research group of hornbill public examination;

The focus of this announcement falls onPhysical examination and investigationupper/better/previous/a surname, that is, in the preparation session.In the part of political review, the main investigation is the personal political position.

Therefore, if students want to enter the public service, they can’t have anything that goes against public order and good customs and ethics.

Second, the interview questions are professional and differentiated.

In-depth promotion of grading and classification examinations, distinguishing the different characteristics of institutions at or above the municipal level and below the county level, will separately order written examination questions for public subjects. According to the nature and characteristics of the work of public security, prisons and other organs, the civil service interview is organized and implemented by classification. In accordance with the requirements of building a high-quality professional civil servant team, we will increase the intensity of professional ability testing, and will conduct professional tests on candidates for 286 positions with strong professionalism to further improve the quality of candidates. Explore the difference investigation, highlight the suitability of people and posts, choose people by things, and avoid simply taking people by points.

Interpretation of teaching and research group of hornbill public examination;

The announcement of this year’s recruitment is inclined to specialization.

Posts with small language requirements require higher professional ability. Total score ratio = language 50%+ test 25%+ application 25%.

In law-related positions, the proportion of requirements for line testing has increased. Total score ratio = legal 30%+ test 40%+ application 30%.

Third, it tends to be grassroots experience and fresh graduates.

Except for some special positions, provincial authorities will mainly recruit people with more than 2 years of grassroots work experience; Organs below the county level will recruit 1021 civil servants specially for college graduates, encourage and guide outstanding college graduates to apply for grass-roots positions, and make contributions to the grass-roots front line. The province will recruit 115 civil servants to serve grassroots project personnel and retired soldiers of college graduates who have served in the military for more than 5 years. At the same time, 151 retired military personnel were recruited. The recruitment of grass-roots civil servants for local outstanding talents, such as secretaries of grass-roots party organizations and long-term township (street) staff, will be organized and carried out separately according to the actual situation.

Interpretation of teaching and research group of hornbill public examination;

This time, the inclination of the grass-roots units was announced.Bigger, whether it is the attention of grass-roots work experience or the tilt of one’s position to the grass-roots level. andProvide more jobs for fresh graduates, and the proportion of fresh graduates is 14.4%.

Fourth, solve the employment pressure and provide humanized recruitment.

In response to the impact of the epidemic, the online registration time has been extended to facilitate candidates to apply for the exam. At the same time, establish a registration tolerance mechanism. If you have not obtained the qualification certificate required by the recruitment position yet, you can register for the exam first after the applicant has made a commitment to provide the qualification certificate before the deadline for qualification examination; Failing to provide it before the deadline for qualification examination, the recruitment agency shall cancel the qualification for application or employment.

Expert interpretation:

aim atDue to the epidemic this year, many qualification examinations are delayed indefinitely, so if there is a qualification certificate requirement, this provincial examination will give you fault-tolerant time.

Fifth, the form and score of the interview have changed greatly.

The exam announcement pointed out thatInterviews take many forms, such as structured interviews.

Interpretation of teaching and research group of hornbill public examination;

The original text of last year’s announcement was that interviews were mainly structured interviews. What’s the difference between those two? One is the structured interview, then the others are supplemented. This was last year, and this year, we were told directly that structured interviews and other forms were adopted.

In the past, the national examination was mainly structured interviews, and there were few others. Now, structured interviews, structured group interviews, and interviews without leading groups are basically equal, so the national examination is a weather vane.

We can predict that other provinces will also keep up with the diversified examination forms of interviews.

Last year, our written test and interview still accounted for 50% of the provincial exams in Shandong Province. This year, the written test only accounted for 40%, and the interview accounted for 60%. The proportion of the exam tilted towards the interview.

The number of candidates in Shandong province is the largest in previous years, and it is also known as the small country exam. Candidates who prepare for the exam can adjust their preparation strategies from the direction of announcement interpretation. Finally, I wish all candidates can get to be no.1 and get good grades in the provincial exams!

　　At the 2022 Global Industrial Internet Conference held in Shenyang, the staff of the participating enterprises demonstrated the industrial Internet platform for garment customization. Xinhua News Agency reporter Wang Yijie photo

　　Visitors visited the exhibition hall of "2022 China 5G+ Industrial Internet" held in Wuhan. Xinhua News Agency reporter Cheng Minshe

　　According to the latest data from the Ministry of Industry and Information Technology, the scale of China’s industrial Internet industry is expected to reach 1.2 trillion yuan in 2022, providing strong support for high-quality economic and social development. The reporter learned from many aspects that China will further improve the top-level design, make full use of fiscal and taxation policies, promote enterprises to actively use 5G and other technologies to carry out digital transformation of factories, accelerate the scale development of industrial Internet, promote the deep integration of digital economy and real economy, and continuously release the power of industrial upgrading.

　　Empowering the transformation and upgrading of traditional industries

　　As a key path to promote the deep integration of the digital economy and the real economy, the industrial Internet continues to release effects in promoting the transformation and upgrading of traditional industries.

　　Industrial Internet logo analysis system is the foundation of industrial Internet network system and an important link to support industrial Internet. In 2022, China’s industrial Internet logo analysis system was fully completed.

　　Zhao Zhiguo, director of the Information and Communication Administration Bureau of the Ministry of Industry and Information Technology, said that at present, all the top-level nodes and two disaster recovery nodes in the five countries in the east, west, north and south are online, and the second-level nodes have achieved full coverage, serving nearly 240,000 enterprises, and cultivating more than 240 influential industrial Internet platforms, including 28 cross-industry and cross-domain platforms, which have effectively promoted data interoperability and resource coordination in the whole product process, production links and upstream and downstream of the supply chain, and accelerated the digital transformation of enterprises.

　　From the perspective of the transformation of the empowerment industry, China has built a number of application promotion service carriers for the common needs of the industry, cultivated "low-cost, lightweight" solutions, and lowered the threshold for digital transformation of enterprises, especially small and medium-sized enterprises.

　　"We focus on the characteristics of various industries, formulate and promote industrial Internet convergence application guidelines for more than 10 key industries, such as steel and electronics, and guide industrial enterprises to develop industrial Internet applications according to their respective industries and enterprises. We implemented the industrial Internet innovation and development project, accelerated the research and industrialization of key technology products, and issued a number of national standards, industry standards and group standards to further improve the standard system. " Zhao Zhiguo said.

　　It is worth mentioning that in the construction and application of "5G+ Industrial Internet", China has built more than 4,000 "5G+ Industrial Internet" projects in more than 10 key industries such as automobiles and mining, and accelerated the popularization of 20 typical application scenarios such as collaborative R&D design and remote equipment control, which effectively promoted enterprises to improve quality, reduce costs and increase efficiency.

　　Zhao Zhiguo introduced that industrial 5G converged products are increasingly abundant, and the price of modules is 80% lower than that in the initial stage of commercialization. All localities have set off a boom in the construction of 5G fully connected factories, accelerating the further deepening and expansion of 5G to the core control link of production.

　　Combined measures to accelerate large-scale development

　　In the eyes of the industry, China’s industrial Internet development is in a critical period of initial exploration and scale development, but it still faces challenges to improve the coverage and application depth of industrial Internet.

　　Zhao Gang, president of Saizhi Industrial Research Institute, believes that in terms of platform applicability, there are many types of industrial enterprises and complex technological processes, and how to adapt the general industrial Internet platform to the application needs of different enterprises needs further exploration. In terms of system application, the production equipment of industrial enterprises may come from different manufacturers, the interface standards of equipment are not uniform, and some systems are still relatively closed, which puts forward higher requirements for system integration. In terms of construction cost, the construction of industrial internet involves the procurement and deployment of sensors, communication modules and network equipment, and industrial enterprises, especially small and medium-sized enterprises, are facing problems such as "lack of technology, lack of talents and lack of funds".

　　The reporter noted that in this regard, relevant departments will make efforts from the aspects of excellent environment, innovation and strong application to accelerate the large-scale development of industrial Internet.

　　Zhao Zhiguo said that the Ministry of Industry and Information Technology will study and formulate policies and measures to promote the large-scale development of industrial Internet, further improve the top-level design, make full use of fiscal and taxation policies, strengthen the integration of production and education, and further create a good development environment. Strengthen technological innovation, implement the industrial Internet innovation and development project in depth, improve the standard system, and crack the key shortcomings that restrict large-scale development; Deepen industrial innovation, support telecom enterprises, Internet platform enterprises, industrial enterprises and other market players to give full play to their respective advantages, strengthen linkage and coordination, vigorously cultivate leading industrial Internet enterprises and "specialized and innovative" small and medium-sized enterprises, and create a healthy and sustainable industrial ecology.

　　At the same time, the popularization of industrial Internet will be further accelerated. Zhao Zhiguo said that it will speed up the cultivation of advanced factories, promote enterprises to actively use technologies such as 5G to carry out digital transformation of factories, and promote the wide application of new technologies, new scenes and new models. Accelerate the upgrading of industrial clusters, carry out the "Hundred Cities and Thousand Parks" activity of industrial Internet, summarize and promote successful cases, and promote the digital and green development of industrial parks. Deepen the expansion of key industries, extensively carry out the docking of supply and demand, and strengthen the popularization of industrial Internet in key industrial chains.

　　Continue to promote the upgrading of industrial Internet files.

　　The industry believes that in the next step, it is necessary to combine the needs of digital transformation of the industry, focus on professional deep cultivation, cross-border financing and cooperation, strengthen technological innovation and network security, and promote the upgrading of industrial Internet to provide support for digital transformation.

　　Yu Xiaohui, president of China Information and Communication Research Institute, said that it is necessary to further support enterprises to deepen their professional capabilities and build an internationally competitive industrial Internet platform. Encourage platform enterprises to make full use of the vast advantages of China’s market, enrich their own digital, modular and platform-based manufacturing resources in service enterprises, incubate professional industrial apps, and develop large-scale promotion applications. Give play to the guiding role of financial funds, incite more social capital to invest in platform industries, support platform enterprises to make rational use of financing funds, realize the accumulation of core technologies through mergers and acquisitions, joint ventures, etc., and promote the cross-industry, cross-field and cross-regional deepening application and promotion of advantageous platforms.

　　In terms of continuously strengthening technological innovation, Yu Xiaohui suggested, on the one hand, focusing on promoting the development and application iteration of industrial mechanism models and improving the basic technical support level of industrial Internet platforms. On the other hand, relying on the network of innovation centers, we will accelerate the incubation of original technologies, carry out innovation incubation around digital twinning, real-time simulation and edge intelligence, and accelerate the sharing and utilization of platform innovation resources nationwide.

　　Zhao Gang said that the next step is to deepen the research and development of customized templates for industrial Internet in different industries, and develop industrial Internet solutions that meet the characteristics of different industries such as machinery, electronics, automobiles, materials and equipment to meet the common needs of industrial enterprises; Second, it is necessary to strengthen the standardization of industrial Internet and realize the integration and data sharing of different devices and systems; Third, it is necessary to strengthen the construction of industrial Internet security system to ensure the network and data security of enterprises.

Topic: Welcome to The 17th National Congress of the Communist Party of China

　　Rooting in fertile soil and working hard ―― Modern distance education for cadres in rural party member has been carried out in depth.

　　　　On April 28th, the National Conference on Modern Distance Education for Rural party member Cadres was held in Beijing. Member the Political Bureau of the Communist Party of China (CPC) Central Committee, Secretary of the Secretariat of the Central Committee, Minister of the Organization Department of the Central Committee, and He Guoqiang, leader of the National Leading Coordination Group for Modern Distance Education for Cadres in Rural party member, attended the meeting and delivered a speech. Xinhua News Agency reporter Gao Jieshe

　　　　Xinhuanet Beijing, September 30th (Reporter Li Yajie) Zhang Xueying, a farmer from Zhengchang Village, Tunzi Town, Xunxian County, Henan Province, used the modern distance education information service station in the village to post her own stone carving works online. In June this year, a scenic spot in Jidong County, Heilongjiang Province signed a stone carving work with her with a total value of more than 4 million yuan, equivalent to four times the amount of orders she received in the past year. She boasted to everyone: "Distance education really helped me a lot."

　　　　In view of the fact that being a pilot in the central region is more important than rural areas and the task of developing distance education is heavy, Henan actively explores new ways to develop modern distance education in line with local conditions. At present, more than 47,000 terminal receiving stations have been built and opened, which are vividly called "through train" to publicize the Party’s principles and policies, "booster" to improve the quality of cadres in rural party member, and "heart-to-heart bridge" to close the relationship between the party and the masses.

　　　　Since the development of modern distance education for cadres in rural party member, cadres and masses in rural party member have been able to hear the voice of the CPC Central Committee and learn the relevant principles and policies of the central government without leaving the village, which has narrowed the distance between the central government and the rural grassroots and promoted the smooth implementation of the Party’s principles and policies in rural areas to thousands of households. At the same time, the cadres and the masses in rural party member obtained information, changed their ideas, developed production, and achieved great economic benefits, which provided strong support for the construction of new socialist countryside.

　　Pilot first scientific planning and classified implementation

　　　　At the beginning of 2003, in order to conscientiously implement the spirit of the 16th National Congress of the Communist Party of China, and actively explore effective ways for rural party member cadres to receive regular education and benefit farmers for a long time, the central government decided to start the pilot project of modern distance education for rural party member cadres in Shandong in the east, Hunan in the middle, Guizhou in the west and Jinzhai County in Anhui Province.

　　　　At the beginning of 2005, the pilot areas were expanded to nine provinces and regions, including Shanxi, Liaoning, Jilin, Heilongjiang, Jiangsu, Zhejiang, Henan, Sichuan and Xinjiang. By the end of 2006, the whole pilot project was basically completed. After nearly four years of pilot work, more than 200,000 terminal sites have been built, nearly 40,000 teaching materials and courseware have been integrated and developed, and a backbone team of 300,000 people has been established, with more than 200 million rural party member cadres and farmers receiving education and training.

　　　　Through modern distance education, the cadres and the masses in rural party member in the pilot areas have improved their comprehensive quality, enhanced their ability to start a business and become rich, and further strengthened the relationship between the party and the masses.

　　　　With the approval of the Central Committee, the National Conference on Modern Distance Education for party member Cadres in Rural Areas, held on April 28th this year, made a comprehensive arrangement for developing modern distance education for party member cadres in rural areas throughout the country. On July 4th, the General Office of the Central Committee of the CPC issued "Opinions on Developing Modern Distance Education for party member Cadres in Rural Areas of China". The central government’s overall arrangement for the modern distance education of rural party member cadres is: from the second half of 2007 to the end of 2010, it will take three to four years to basically build a modern distance education network system for rural party member cadres throughout the country, complete the task of infrastructure construction, and basically achieve full coverage of sites in towns and villages.

　　　　According to this overall goal and local conditions, all localities have promoted various constructions step by step. The three provinces that were piloted in advance further consolidated and improved the management and use level of the established sites. Shandong decided to establish a centralized study day system for cadres in rural party member in an all-round way, and started the implementation of the "party member cadres’ modern distance education project to get rich through science and technology"; Hunan carried out the model of distance teaching and the selection of "Yuan Longping Science and Technology Award" to promote the in-depth development of learning and application; Guizhou has made great efforts to build a number of excellent demonstration sites of "village-school combination" and continuously improve the level of distance education in the province.

　　　　Nine provinces and autonomous regions that have expanded the pilot project will speed up the construction progress on the existing basis, realize full site coverage in towns and villages by the end of 2008, and carry out work in improving the mechanism, strengthening management and deep chemical utilization. In accordance with the principle of "integrating resources, co-constructing and sharing", Henan has further explored the methods of joint construction of infrastructure, joint investment of human resources, joint production of teaching materials and courseware, and joint efforts of education and training to further promote modern distance education.

　　　　According to reports, the 19 provinces, autonomous regions and municipalities and Xinjiang Production and Construction Corps that have started this work will complete the task of infrastructure construction by the end of 2010 and achieve full coverage of sites in towns and villages. The eastern region will appropriately accelerate the pace of construction, and the central and western regions will steadily promote various constructions according to actual conditions.

　　Learning policy broadens one’s horizons and leads to wealth.

　　　　"Hello,’ Director Shi’? My family’s Kaite apricot is going to go to the greenhouse. Is there a program on this?" Early in the morning, Shi Chengguan, a distance education administrator in Shijia Village, Pingyi County, Shandong Province, received a phone call from the villager Chu Yongcai. "As it happens, the distance education program has just downloaded the greenhouse cultivation technology of Kaite apricot, and it will be broadcast until 10 o’clock for you. What do you think?"

　　　　In the summer of 2004, a reception site for modern distance education for rural party member cadres was built in Shijia Village, and the rich and colorful content of distance education programs became the "golden key" for villagers to get rich. When the administrator becomes an official, he insists on downloading distance education programs every day and organizing party member people to study and watch them at least once a week. In order to meet the individual needs of farmers, the village invested in new professional equipment, laid cables and delivered distance education programs to every household, which was affectionately called "Distance Education TV Station" by farmers. In order to enrich the content of the program, the village also purchased more than 3,000 educational CDs as auxiliary teaching materials. After the opening of "Distance Education TV Station", it was warmly welcomed by the peasants. Anyone who wants to watch any program can just call the administrator.

　　　　Since the opening of the "Distance Education TV Station" in Shijia Village for three years, it has brought benefits to the peasants in the village, and the feelings between cadres and the masses have also drawn closer. Shi Chengxue, who has been the secretary of the village party branch for many years, said with emotion: "It is distance education that has brought me a panacea and taught me how to be a good village cadre!"

　　　　Around the central government’s major decision-making, major activities and key work, all localities have organized the production of learning materials for the key, difficult and hot issues concerned by rural party member cadres and farmers, and timely carried out special education and training to give full play to the role of modern distance education for rural party member cadres.

　　　　In the activities of advanced education, grass-roots party organizations around the country use modern distance education to organize party member to study, which enhances the attraction and improves the participation rate. In the process of promoting the construction of new socialist countryside, modern distance education network system has been used in various places to publicize and educate the policies, measures and experiences of the rural party member cadres and farmers, which has increased the talents of rural cadres and party member and trained a group of new farmers who are literate, know technology and can operate.

　　　　In view of the fact that local farmers lack ideas and methods to get rich, Ningbo City, Zhejiang Province produced "Thirty-six Strategies for Rich Villages", which was very popular after broadcast. The Party branch of Alashan Village, xinyuan county, Xinjiang, organized local herdsmen to watch the technical training materials of "Mujiale" tourism and catering service at the receiving site, which solved their problems of ideological emancipation and technical training difficulties and promoted the development of tourism. In 2006, there were 20 "Mujiale" in this village, and the monthly net income of each family reached more than 5,000 yuan in the golden season of tourism.

　　　　In order to welcome the victory of the 17th National Congress of the Communist Party of China, various localities have also produced a number of special propaganda films that are loved by cadres and the masses in rural party member.

　　　　Shandong organized and produced a set of special talk shows, which were used as the necessary teaching materials for the intensive study in rural party member. Jilin organized and produced a special program "Representative Style" to focus on publicizing the representatives of the 17th CPC National Congress from the grassroots. Xinjiang used "Xinjiang Kunlun Net" to broadcast "Song of Communist party member" to create a good atmosphere for the victory of the 17th CPC National Congress.

Editor: Li Xingchi