Due to the lack of special drugs for children, many children are treated as "miniature adults" when taking drugs. Adult drugs are given to children according to the principle of "children should be reduced at their discretion", and the dosage depends on breaking and guessing. To solve the problem of children’s safe drug use, it is necessary to mobilize all sectors of society to give full play to their respective functional advantages and let children use children’s drugs — —

　　The recently released White Paper on Children’s Drug Safety Investigation Report in 2016 shows that about 30,000 children in China are deaf every year due to improper drug use. This figure shows that improper drug use by children not only hurts children, but also brings many misfortunes to families and a heavy burden to society.

　　A few days ago, at the 2017 Children’s Medication Safety Summit Forum jointly sponsored by Children’s Medication Safety Branch of China Medical News Information Association and Beijing Children’s Hospital affiliated to Capital Medical University, experts pointed out that due to the lack of special drugs for children, many children were treated as "scaled-down adults" when taking drugs. According to the principle of "children’s discretion", the use of adult drugs for children was reduced, and the dosage was determined by guessing. "There is a huge safety hazard in doing this, and children should use children’s medicine."

　　Children’s exclusive drugs are less than 2%

　　Recently, the reporter visited a number of pharmacies in Beijing and found that many of the common pharmaceutical preparations in the market do not have children’s dosage forms, and children’s special drugs are very scarce. Ms. Liu Hua told reporters that her daughter is three years old this year. Every time she goes to the hospital to see a doctor, she has to do "calculation problems" when she goes home. "The doctor said that children should take less medicine, and they usually take an adult medicine several times. Parents of larger tablets are handcuffed. If the tablets are small, they need to crush them with tools, and then estimate the dose and divide it into several parts for children to take with warm water. " Liu Hua said that compared with adults, children use drugs very little.

　　Zhao Zhigang, director of pharmacy department of Tiantan Hospital affiliated to Capital Medical University and chief pharmacist of Beijing Hospital Authority, said that there are about 180,000 drugs with approval numbers in China, and more than 3,000 drugs are used by children, accounting for less than 2%, involving only more than 400 varieties. This is far from enough compared with the number of 220 million children in China and the prevalence rate of 12%. The dosage forms and specifications suitable for children are also very scarce, especially for young children and newborns. According to the survey of Beijing Children’s Hospital affiliated to Capital Medical University, among 231 kinds of commonly used prescription drugs for children, the top three dosage forms are injections, tablets and oral liquid, among which the dosage forms suitable for children, such as powder inhalers, suppositories and syrups, are very few.

　　Because of children’s vigorous metabolism and poor adjustment ability, their sensitivity to drugs is higher than that of adults, but a large number of drugs are lacking in children’s usage and dosage, and there are few special drugs for children. The incidence of adverse drug reactions among children in China is high. Zhao Zhigang said that the adverse drug reaction rate of children in China was 12.9%, and that of newborns was as high as 24.4%, which was 2 times and 4 times higher than that of adults. The adverse drug reaction report recently released by the State Food and Drug Administration shows that in 2016, the number of children under 14 years old (inclusive) accounted for 10.6% of the total report, of which serious adverse drug reactions accounted for 5.5% of the total report of children.

　　Drug research and development into a short board of enterprises

　　Why are there so few special drugs for children? Bian zhenjia, a special researcher in the State Council Counselor’s Office, said: First, the policies are not matched, and the relevant systems of supervision and use are not connected. The marketing approval of children’s drugs is in the food and drug administration department, the policy management is in the health department, the clinical use is in medical institutions, and the reserve management is in the industry and information department. Many parties are responsible for one section, and the relevant systems and standards are not matched, unified and out of line. Second, the clinical trial process is risky, which affects the clinical development of new drugs. This is also a problem that puzzles the children’s medicine production industry in the world. In developed countries, the premise of clinical trials is to sign an informed consent form with volunteers, insure them with accident insurance and necessary economic compensation, and this is the biggest expenditure on research and development. Third, the marketization of children’s medication is not high, the profits of pharmaceutical companies are low, and the enthusiasm for production is not high. At present, the number of children in China and the annual consumption of sick drugs are basically stable, and there is little room for the expansion of the children’s drug market; Children are not miniature versions of adults, their organs are immature, their onset characteristics, process, absorption mechanism and compliance are different, and they also need special formulas, preparations and tastes, which makes the R&D and production process of drugs more complicated and the cost higher, which leads enterprises to be unwilling to engage in the R&D, production and marketing of children-specific drugs.

　　According to the data from China Pharmaceutical Industry Information Center, there are 8,812 pharmaceutical manufacturers in China, of which only 0.1% are specialized in the production of drugs for children. In the drug clinical trial registration project, the registered information of domestic drugs reached 165,151, of which only 2,698 were children’s drugs, accounting for only 1.63%. Children’s drugs registered in clinical trials only account for 2.35%, which is too little compared with the proportion of more than 20% in developed countries such as the United States.

　　"Because the pricing principle of children’s medicine is based on the content of active ingredients, the content of active ingredients of children’s medicine is much lower than that of adult medicine, and the corresponding selling price is lower than that of adult medicine, which makes children’s medicine have no obvious advantage in pricing, and enterprises cannot get compensation." Chen Baohua, general manager of Zhejiang Huahai Pharmaceutical Co., Ltd. said that in order to solve the problem of shortage of drugs for children, experts from professional associations can summarize the epidemiological situation and the current situation of children’s drug use in China, determine which pediatric diseases need to be overcome urgently, and formulate a list of children’s drugs to encourage research and development according to domestic and foreign pediatric drug use guidelines and clinical experience, implement priority review and approval, and guide enterprises to research and development.

　　In addition, relevant experts found in the research that domestic children’s drug instructions generally lack pharmacokinetic data, and even if there are, most of them are foreign children’s data. In some domestic drug instructions, the data of children’s clinical trials basically copy the instructions of imported original drugs. According to experts, there are differences between children and adults, and between children from different countries. China children’s clinical trial data is needed to make the efficacy more accurate, but China’s clinical data is far from enough.

　　Encourage the development of children’s medicines.

　　"In order to protect children’s health rights and encourage children’s drug development. In recent years, various departments have formulated various policies on the protection of children’s medication. " Feng Zhang, deputy director of the Department of Pharmacy Administration of the National Health and Family Planning Commission, said that since last year, the Health Planning Commission, the Ministry of Industry and Information Technology and the Food and Drug Administration have published two batches of 71 varieties of children’s drugs to encourage research and development, and made it clear that the drugs in the "list" have been used for many years in Hong Kong, Macao and Taiwan, which are clinically effective and safe to use, but are not listed in the mainland. Explore the pilot import and use of drugs, and allow direct reference to the clinical drug use data of children in Hong Kong, Macao and Taiwan as the basis for declaration when registering and reviewing imported children’s drugs. In addition, through the national "major new drug creation" major science and technology projects, major innovation and development projects for protein biopharmaceuticals and vaccines, we will integrate superior units to collaborate in innovative research and development, and guide and encourage enterprises to give priority to R&D and production; In terms of ensuring production and supply, we will give policy support to the corresponding children’s drug production enterprises and promote product upgrading and technical transformation of production lines.

　　Wang Tianyou, secretary of the Party Committee of Beijing Children’s Hospital, said that clinical trials of children’s medication are facing difficulties such as difficult evaluation, high evaluation risk, difficulty in recruiting subjects and lack of professionals. During the 13th Five-Year Plan period, Beijing Children’s Hospital will unite a number of units to further strengthen the construction of clinical evaluation support system for children’s demonstration new drugs, and improve the ability of clinical evaluation of children’s drugs through the construction of key technology platforms for children’s drug clinical trials and the construction of key technology platforms for children’s drug big data clinical evaluation. Three clinical specialties were selected as representatives of common diseases, major diseases and rare diseases in children, and a demonstration platform for clinical evaluation of new drugs for children was established.

　　At the same time, Ceng Yixin, deputy director of the National Health and Family Planning Commission, said that the National Health and Family Planning Commission and other six departments have issued several opinions on the protection of children’s medication and formulated two batches of lists to encourage research and development. Especially in the national major special projects of new drug development, the research and development of children’s drugs and speeding up the examination and approval have been taken as key tasks. "Drugs suitable for children should have appropriate doses according to the weight of different children; The dosage form should be in the form of oral liquid; And it should be suitable for children’s tastes and make them willing to drink. This is ‘ Thirteenth Five-Year Plan ’ Key tasks, the Ministry of Science and Technology, the Ministry of Finance, the Food and Drug Administration, the Health Planning Commission and other joint efforts to speed up the research and development and approval procedures for drugs specially suitable for children in China. It is estimated that the shortage of medicines for children will be effectively solved in a few years. "

　　"The healthy growth of children is related to the harmony and happiness of each family and the healthy progress and sustainable development of the nation." Feng Zhang said that to break the problem of children’s safe drug use, it is necessary to mobilize all sectors of society to give full play to their respective functional advantages, including government agencies, social organizations, enterprises, hospitals, media, etc., and at the same time, it is also necessary to spread and educate children’s scientific drug use knowledge.

On September 10th, Extreme Yue 07 was officially launched. Extreme Yue Automobile was jointly built by Geely Group and Baidu Group. Extreme Yue 07 is the second model of the brand, and it is also a medium and large pure electric car. There are three versions of the new car, with a price range of 209.9-299.9 thousand yuan and a limited cash discount of 10,000 yuan.

Mr. Xia’s joke "Extreme Yue 07 is Model 5 that Tesla didn’t make" is just a joke, but it does make it easier for users to understand the positioning of this product. It is a new generation product with larger size and more advanced technology, which pays attention to driving experience and adopts visual intelligent driving scheme.

Extreme Yue 07 canceled the design of the door handle, the radar round hole and wiper were designed in a hidden way, and at the same time, it was equipped with an automatic lifting electric tail, which matched with the diffuser surrounded by blackened bottom, giving a full sense of movement, and at the same time, the wind resistance was 0.198Cd lower, which was at the leading level in the industry.

In terms of body size, the length, width and height of Extreme Yue 07 are 4963mm/1989mm/1475mm, and the wheelbase is 3013 mm. The wheelbase exceeding 3 meters also brings extremely spacious seating space in the car. In addition, the hatchback tailgate with the largest opening at the same level is adopted, which can reach 581L in normal state and 1573L after the second discharge, and can put down a 1.5m-meter-wide double mattress.

Extreme Yue 07 also launched six colors simultaneously: deep space black, space silver, aurora green, galaxy purple, technology white and titanium crystal gray.

If Yan value is just "superficial kung fu", another bright spot of Extreme Yue 07 is enough to make it stand firm. As the first intelligent driving car in the AI era, Extreme Yue 07 is the first to take the advanced ASD Apollo intelligent driving of Baidu, with "pure vision+end-to-end big model" opening a new stage of intelligent driving development.

In terms of hardware, Extreme Yue 07 is equipped with dual NVIDIA DRIVE Orin chips, and Al finally has 508 TOPS, and is equipped with 28 intelligent driving sensors, including 11 high-definition cameras, 12 ultrasonic radars and 5 millimeter-wave radars, which support high-order intelligent driving functions such as high-speed navigation and urban road navigation.

In other respects, the Extreme Yue 07 is also equipped with the industry’s first automatic turn signal and automatic shift function. After the vehicle recognizes the road condition, AI automatically recognizes the driving intention, and the owner can automatically put on the brake and get on the bus and leave. Whether intelligent driving is turned on or not, the vehicle can automatically turn on the turn signal in advance after recognizing the turning road conditions.

Of course, Extreme Yue 07′ s investment in intelligence goes far beyond intelligent driving, and there is also an intelligent cockpit. It is equipped with a 35.6-inch 6K giant screen, which can take into account the functions of instrument panel, central control screen and auxiliary driving screen. It is equipped with 8295 car chip and newly upgraded SIMO 2.0, which can realize the only lip movement recognition function in the industry. By fusing and identifying the user’s lip movement trajectory, the accuracy of speech recognition in noisy environment is improved to 90%.

The interior is surrounded by starship ambient lights, including 188 ambient lights, 256 colors, the fifth-generation U-shaped steering wheel, and a liftable ROBO SOUND speaker. It has 7.1.2 speaker layout with sky channel /16-channel independent power amplifier /18 hi-fi speakers, including subwoofer, main driver headrest stereo and tailgate surround speaker.

There is also a 1.96㎡ super-large stargazing dome, which can achieve 99.9% ultraviolet isolation rate and 99.1% infrared isolation rate, and truly meet the needs of users with all-round canopy, vision, sun protection and communication.

Specifically, the Extreme Yue 07 has launched three models. The standard version of the Extreme Yue 07 is 400V architecture, equipped with a rear single motor, with a maximum power of 200 kW and a CLTC cruising range of 660km；. The "King of Endurance Cost-effectiveness" Extreme Yue 07 Long Endurance Edition is 800V architecture, and CLTC has a maximum endurance of 880km. Extreme Yue 07 Performance Edition is equipped with dual-motor four-wheel drive system, with 100-speed acceleration of 3.5s and CLTC cruising range of 770km.

Based on the vast architecture of Geely SEA, Extreme Yue 07 has inherent control advantages, including front all-aluminum double wishbone/rear all-aluminum H-Arm multi-link independent suspension, Brembo four-piston fixed calipers, and a real-time damping adjustable vibration reduction system with 500 responses per second. In addition, Extreme Yue 07 has specially set up a track mode, and users can drift with one button and change drivers in seconds.

As a pure tram, it is necessary to have a good battery. The battery pack adopted by Extreme Yue 07 is a breakthrough new product of Contemporary Amperex Technology Co., Limited. At the same time, with 800V silicon carbide technology, the comprehensive efficiency of electric drive can reach 96.5%, the maximum power can reach 530kW, the zero acceleration of 3.5s seconds and the speed of 230km/h, the power consumption per 100 kilometers is only 12.4 degrees, and the battery can be charged for 10 minutes for 600km, which really realizes one second.

No doorknob doesn’t mean it’s unprotected. On August 25th, Extreme Yue 07 completed a car-destroying collision challenge. After the triple collision of 60km/h in the front and tail and 30km/h in the side, the doors of Extreme Yue 07 were severely deformed, but the four doors of Extreme Yue 07 could still actively provide 5000N unlocking force, which was equivalent to the gravity of half a ton of objects and could be easily opened.

In the collision challenge, there was no fire and smoke in Polar Yue 07, so how did Kirin battery achieve such a high standard? Kirin battery adopts bullet-proof and extremely high safety coating, which has high elastic modulus, high tensile strength, high ductility and excellent impact resistance. In addition, in the shooting test of live ammunition, it also shows the characteristics of no fire, no deformation and no explosion, which truly realizes high safety.

Write at the end:

Extreme Yue 07 enjoys the advantages of Geely, Baidu and Contemporary Amperex Technology Co., Limited, which can be said to have unlimited potential. Did Extreme Yue 07, which combines a series of keywords such as long battery life and high-order intelligent driving, impress you?

● Article 8 Car logo: 1972-1984

　　When it was sold to Birmingham Company in aston martin in 1972, because the helm of the company was changed to William Willson, the word "David Brown" appeared on the aston martin logo was obviously inappropriate, so a new aston martin logo was born. In addition to the letter "David Brown", the feathers on the logo were "combed" again, the lines on the inner and outer layers were connected into a whole, and the background of the logo turned light blue. This logo was first installed on V8 models after 1972. Subsequently, the V8 and models also used brand-new logos.

　　Since 1974, aston martin has been in turmoil again. In 1975, it was taken over by North American Peter Sprague and Canadian George Minden. In 1981, it was taken over by a private oil company led by Victor Gauntlett; In 1983, it was 100% acquired by the American distributor Automobile Investment Alliance; In October 1984, the Peter Livanos family owned 75% of the shares, and Victor Gauntlett owned the remaining 25%. It was not until 1987, when Auto acquired 75% of aston martin’s shares, that aston martin’s fate was temporarily calmed down. In 1994, Ford owned Aspen.
All the shares of don Martin.

● The ninth logo of aston martin: 1984-2002

　　During the turbulent years in aston martin, the logo of aston martin has undergone a change, which was in 1984, after the Peter Livanos family owned aston martin. At that time, the models produced in aston martin were still V8 and V8 Vantage. In that year, the 10,000 th model of aston martin rolled off the assembly line, so aston martin put on a brand-new logo. Of course, the change of this logo is still "changing the soup without changing the medicine", mainly for the internal lines and borders of the logo feathers. The interior of the logo has become more concise and the borders have become silver again.

　　After entering Ford, aston martin began to develop and launch a large number of new models. Not only did the DB naming method, which had been stopped for nearly 20 years, be re-launched in 1993, and DB7, DBS, DB9 and other models were launched respectively, but also brand-new V8, V8 Vantage, V8 Zagato and other models were launched, and the sales volume also increased gradually. In a few short years, the sales volume of aston martin was higher than the sum of the models produced in the past 80 years.

● Aston martin Tenth Car Logo: 2003-Up to now

　　2003 is an unusual year for aston martin, which is not only the 90th anniversary of the founding of aston martin Company, but also the new V8 Vantage released by aston martin at the north american international auto show held in Detroit, Michigan, USA, which reintroduced the classic V8 and greatly enhanced the company’s market competitiveness. At the same time, the DB9 model came out, replacing the DB7 model for ten years. In addition, in the same year, a new factory was established in Gordon, England, becoming the first professional factory in the history of aston martin. It was also in this year that the latest generation logo of aston martin, which you see now, was born.

　　The last time aston martin changed hands was in 2007, when a consortium led by British David Richards bought it from Ford at a cost of $959 million. That is to say, aston martin has returned to her native Britain again after years of travelling in other countries.

● The centenary of aston martin: 2013.

　　Today, all the models in aston martin still carry the logo of DB9. At the same time, on September 29th last month, aston martin also launched a centennial logo (only used by Aston Martin brand to celebrate its centenary birthday in 2013), which was designed by Marek Reichman, the design director of Aston Martin, and will be put into use in 2013 to commemorate the glorious centennial history of this classic luxury brand.

Summary:

　　In fact, since the second logo of aston martin, all the logos have kept a theme, that is, spreading a pair of wings, which was very popular in the era when the automobile industry just started. Today, after nearly a hundred years of ups and downs and evolution, aston martin logo is still full of design sense, and it is not out of date, and the previous design style has been completely passed down. Of course, it is not only the logo design that has been passed down, but also the brand of "high-quality car with high performance and perfect appearance" produced in aston martin. (Text/Figure Zhang Wenjun)

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> > Click on car home Culture Team to enter the interesting world of automobiles < <

　　● In the buyer’s show of a store, many netizens showed photos of children wearing lipstick and eye shadow. Some of the main characters in the photos looked like preschool children of four or five years old. The child’s tender face was too rosy because of blush, his eyes were swollen because of pink eye shadow, and his mouth was painted with big red lipstick.

　　● Search for "children’s makeup" and "children’s cosmetics" shows that some cosmetics sold to children and used by children are actually adult cosmetics, which are "fake" children’s cosmetics. In the vicinity of some schools, students can buy eye shadow with sequins, lipstick and other products in the canteen for only a dozen yuan, and these products are not marked with children’s cosmetics.

　　● According to the provisions of the Law on the Protection of Minors and the Regulations on the Supervision and Administration of Children’s Cosmetics, children’s cosmetics must be marked with "precautions" and "special signs", otherwise they may not be sold. It is illegal for a merchant to sell non-children’s cosmetics to children. Obviously, it is impossible to indicate the "children’s cosmetics mark".

　　● In the sales process, it is necessary to strengthen the review of the sales and operation qualifications of e-commerce platforms and retailers. Those who use children’s toys to sell children’s cosmetics without cosmetics business qualifications should be considered as "beyond the business scope" and punished; If ordinary cosmetics are passed off as children’s cosmetics, they will be punished in accordance with the provisions of the Consumer Protection Law.

　　□ Our trainee reporter Ding Yi

　　□ Our reporter Wen Lijuan

　　"How to sell children’s eye shadow in the toy store? Cosmetics have become something that children can buy and use at will &lsquo; Toys &rsquo; ？” This is the doubt of Li Qing (pseudonym), a resident of Chaoyang District, Beijing, during the Spring Festival this year.

　　According to a recent investigation by the reporter, many children are using children’s cosmetics, but some children’s cosmetics are sold in toy stores, and even appear in the canteen around the school. Some of the cosmetics claimed to be used for children do not have children’s cosmetics signs, and they are not written and reminded. Minors need to use them under the supervision of adults.

　　In fact, in order to regulate the production and operation of children’s cosmetics, National Medical Products Administration organized and issued the Regulations on the Supervision and Administration of Children’s Cosmetics. The reporter of Rule of Law Daily conducted an investigation.

　　Toy shops sell children’s cosmetics.

　　No children’s cosmetics logo

　　Li Qing brought some cosmetics such as facial mask, lipstick, eye shadow and liquid foundation for her own use when she returned to her hometown for the Spring Festival this year. As a result, her 11-year-old sister saw it and clamored for "makeup" every day. After careful inquiry, I learned that some girls in my sister’s class in the fifth grade of primary school had biochemical makeup, at least took good-looking art photos, and some even brought pale pink lip balm to school.

　　"Sister envy classmates &lsquo; Exquisite &rsquo; I must teach her how to make light makeup. " Li Qing said.

　　Considering her younger sister’s age is too small and her skin is delicate, Li Qing is worried that her stealing her own cosmetics will cause skin allergy, so she decides to take the initiative to buy children’s cosmetics for her younger sister to use. However, when Li Qing entered "children’s cosmetics", "children’s eye shadow" and "children’s lipstick" in the search box of the shopping platform, he found that many children’s cosmetics sellers were toy stores.

　　After hesitation, Li Qing still placed an order for her sister to buy some children’s cosmetics with good quality, but after receiving the goods, she found that some sequined eye shadows didn’t bear the logo of children’s cosmetics.

　　Zong Jing (pseudonym), a citizen of Jinan, Shandong Province, also bought some children’s cosmetics for her little daughter who went to kindergarten in the toy store on the shopping platform.

　　Zong Jing told reporters that her daughter especially likes to apply makeup such as eye shadow and lipstick to her face.

　　The little girl can’t speak fluently. When asked by a reporter why she likes makeup, she smiled and nodded timidly and said, "Yes, makeup can make me happy."

　　Zong Jing admits that she doesn’t know the ingredients of the children’s cosmetics she bought, but she only sees that the shops claim that it is a cosmetic that children can use. "But these shops don’t specialize in children’s cosmetics."

　　After opening the shopping link of children’s cosmetics given by Zong Jing, the reporter found that this is a toy franchise store, and the name of the link is marked "Toys for little girls aged 3 to 6".

　　The reporter’s investigation found that on the e-commerce platform, there are indeed many children’s cosmetics sets with high sales volume sold in toy stores, such as "XX Baby High-end Toys", with the toy type of "playing house" and the trade name of "XX Children’s Cosmetic Toy Set".

　　In the buyer’s show of a store, many netizens showed photos of children wearing lipstick and eye shadow. Some of the main characters in the photos looked like preschool children of four or five years old. The child’s tender face was too rosy because of blush, and his eyes looked swollen because of pink eye shadow. His mouth was painted with big red lipstick.

　　The cosmetics sold in this shop did not remind children to use them under adult supervision. In the comment area, some netizens asked "Is there a small golden shield (a sign of children’s cosmetics)", and some buyers replied "No". More buyers answered "What is a small golden shield", and some buyers said that there was a little side effect after using it, "The child is a little itchy after wearing eye shadow or blush".

　　According to the Regulations on the Supervision and Administration of Children’s Cosmetics, which came into effect on January 1, 2022, children’s cosmetics refer to cosmetics that are suitable for children under the age of 12 (including 12 years old) and have the functions of cleaning, moisturizing, refreshing and sun protection. Labeling words such as "applicable to the whole population and the whole family" or using trademarks, patterns, homophones, letters, Chinese Pinyin, numbers, symbols, packaging forms, etc. to imply that the product users include children’s products, it shall be managed according to children’s cosmetics.

　　At the same time, China encourages cosmetics operators to display children’s cosmetics in different areas and publicize children’s cosmetics signs in the sales areas. For children’s cosmetics operators in the e-commerce platform and those who operate children’s cosmetics through self-built websites and other online services, information such as cosmetics labels consistent with cosmetics registration or filing materials should be fully, truly and accurately disclosed, and children’s cosmetics signs should be continuously publicized in a prominent position on the product display page.

　　The children’s cosmetics logo "Xiaojindun" was issued by National Medical Products Administration. Since May 1, 2022, children’s cosmetics applying for registration or filing must be marked with the children’s cosmetics logo.

　　In other words, "Little Golden Shield" is a distinctive sign that children’s cosmetics are different from adult cosmetics, disinfection products, toys and other easily confused products. Non-children’s cosmetics may not be marked with this sign.

　　According to Yao Jinju, a professor at the School of Law of Beijing Foreign Studies University and director of the Research Center for Chinese and Foreign Education Law, whether selling children’s cosmetics in physical stores or on e-commerce platforms, the "Little Golden Shield" logo must be marked and publicized, and selling children’s cosmetics that are not marked and publicized on the packaging display surface/page is suspected of violating the law.

　　Adult cosmetics are sold to children

　　It is easy to buy around the school.

　　During the investigation, the reporter found that the results of searching for "children’s makeup" and "children’s cosmetics" showed that some cosmetics sold to children and used by children were actually adult cosmetics, which were "fake" children’s cosmetics.

　　For example, a store on a certain platform sells a "Children’s Day Cosmetic Set", which includes products such as cream, liquid foundation, blush, loose makeup powder, lipstick, 30-color eye shadow tray, eyeliner and mascara. The product is known as "one set!" Multi-scene application. After authoritative testing, you can buy with peace of mind. Plant makeup, my mother is more at ease. "

　　The reporter asked the seller: "Is this children’s cosmetics?" The customer service replied: "The main products are &lsquo; cream, liquid foundation, blush, makeup remover, face cream, lipstick and loose makeup powder; Xiaojindun &rsquo; Logo, others have not been applied for yet. The products are safe and gentle, so you can buy them with confidence. "

　　Because no eye shadow, eyeliner, mascara and other products were mentioned, the reporter confirmed to the customer service whether these products belonged to children’s cosmetics, and the customer service said, "No &lsquo; Xiaojindun &rsquo; Sign ",but" children can use it, which is quite gentle and easy to use, and the customer feedback is good. "

　　A chain big-name online skin care and beauty shop sells a "children’s stage makeup performance makeup kit, eye shadow blush powder cake integrated non-toxic makeup". The reporter asked the customer service: "Does this belong to children’s cosmetics?" The customer service replied, "It’s not children’s cosmetics, no &lsquo; Xiaojindun &rsquo; Sign. " The reporter asked whether the children’s dance class performance program can be used. Customer service said: "It can be used, the makeup will not be light, and the effect is very good."

　　The reporter saw that more than 200 people bought this cosmetic in a week, and more than 900 people bought it. There are more than 290 comments in the comment area, most of which are favorable comments: "I bought it for children to perform, and everything is complete." "I have a full set of makeup tools, including eye shadow, foundation, blush, loose powder, makeup brush and powder puff." "My girl likes it very much."

　　The reporter also visited a number of large supermarkets and skin care cosmetics shops in Chaoyang District and Xicheng District of Beijing, and found that most businesses did not distinguish between children’s makeup and adult makeup.

　　In an adult makeup chain, the reporter said that he would buy children’s makeup for his cousin in elementary school. The clerk said that there is no special children’s makeup, but "it can help to match a box". The reporter asked if there were any side effects, and the clerk said, "Choose something mild that can be used for sensitive skin. Many children buy our makeup for performances, and it makes no difference."

　　The reporter bought a color eye shadow named "sequined eye makeup for children’s performance" in a convenience store, and repeatedly asked the merchant whether the product was specially used for children’s makeup. The other party said "yes". After the reporter paid, he unpacked the goods and found that the goods did not belong to children’s cosmetics, and even the production license number was not written. The business scope of the manufacturer did not include children’s cosmetics.

　　The reporter also found that there are also businesses selling cosmetics near primary and secondary schools in some areas, and businesses sell adult cosmetics to children.

　　In a canteen near a primary school in Shandong province, students can buy eye shadow with sequins for only a dozen yuan, lipstick and other products for dozens of yuan. These products are not marked with children’s cosmetics, and the merchant said that the sales volume is quite good. "Light lipstick sells well, and there is lip balm with color, which will not be discovered by the teacher in class."

　　On a short video platform, a blogger conducted a "cosmetic evaluation of stationery store at the entrance of primary school". At the entrance of a primary school, the blogger bought Floral Liquid Foundation, Makeup Pencil, Cosmetic Household Bucket (Eyebrow Pencil, Eyeshadow, Blush, etc.). After trying Floral Liquid Foundation, she sighed, "God, it’s so silky, even acne marks can be covered, and this is only 19.9 yuan."

　　Can you sell lipstick and eye shadow that are not children’s cosmetics around the school?

　　In Yao Jinju’s view, businesses are not allowed to sell non-children cosmetics to children. According to the Law on the Protection of Minors and the Regulations on the Supervision and Administration of Children’s Cosmetics, children’s cosmetics need to be marked with "precautions" and "special signs", otherwise they may not be sold. It is illegal for a merchant to sell non-children cosmetics to children, and it is obviously impossible to indicate the "children’s cosmetics mark".

　　Zhang Bufeng, a professor at the Law School of Minzu University of China, believes that if such products are children’s toys, that is, products such as "lipstick toys" and "blush toys" produced according to toy standards are not managed as cosmetics, the relevant departments should test the relevant element content of toy materials according to the relevant provisions of the Product Quality Law and relevant standards. At the same time, it should be found out whether the operator has the qualification to deal in cosmetics. If he has not obtained the qualification to sell cosmetics, he is engaged in business activities in violation of regulations.

　　"Operators shall, in accordance with the provisions of the Law on the Protection of Minors, mark the precautions in a prominent position for toys that may endanger the physical and mental health of minors. If they are not marked, they shall not be sold. Those who sell in violation of regulations infringe upon the legitimate rights and interests of minors and cause personal, property or other damage shall bear corresponding responsibilities according to law. " Zhang Bufeng said.

　　Regulatory provisions should be fully implemented.

　　Set up a safe area around the school.

　　In view of the chaos of children’s cosmetics sales, the interviewed experts gave suggestions on governance.

　　"Children include kindergarten children and primary school students. Merchants will use children’s unique psychology to integrate popular cartoons, online games, fashionable toys and other elements into cosmetics packaging, which will arouse children’s curiosity about cosmetics and children’s groups will also influence each other. " Yao Jinju said that the supervision of children’s cosmetics sales should be strengthened.

　　"China’s supervision of children’s cosmetics is very strict, and the" Regulations on the Supervision and Management of Children’s Cosmetics "has been specially issued, with a view to supervising the whole process of children’s cosmetics from production to sales to ensure the safety of children’s use of cosmetics." Zhang Bufeng said.

　　Zhang Bufeng explained that in the production process, we must strictly control the formula design and use of raw materials of children’s cosmetics in accordance with the Guidelines for the Declaration and Evaluation of Children’s Cosmetics and the Quality Management Standards for Cosmetic Production, so as to meet the scientific and necessary production requirements. In the packaging process, urge the responsible person to strictly implement the legal requirements such as "Little Golden Shield", "Attention" or "Warning" in China’s Regulations on the Supervision and Administration of Children’s Cosmetics, and not to label words such as "food grade" and "edible" or food-related patterns.

　　Zhang Bufeng believes that in the sales process, it is necessary to strengthen the review of e-commerce platforms and the sales and operation qualifications of retailers. Those who use children’s toy packaging to sell children’s cosmetics without cosmetics business qualifications should be considered as "beyond the business scope" and punished; If ordinary cosmetics are passed off as children’s cosmetics, they will be punished in accordance with the provisions of the Consumer Protection Law. We should also advocate that sellers have business qualifications, and actively fulfill the legal responsibility of establishing and implementing the inspection and record system of incoming goods and displaying children’s cosmetics in different regions as stipulated in the Regulations on the Supervision and Administration of Children’s Cosmetics.

　　"In the supervision link, the department responsible for drug supervision and management should list cosmetics operators with concentrated sales behavior as key supervision targets in accordance with the principle of risk management, combined with local conditions and according to the sales situation of different businesses, and increase the frequency of supervision and inspection to ensure the safety of children’s cosmetics." Zhang Bufeng said.

　　The interviewed experts believe that the "Regulations on the Supervision and Administration of Children’s Cosmetics" should be fully implemented at present, and the relevant competent departments need to strengthen supervision and inspection and supervise the frequency of sampling inspection, and timely investigate and deal with the illegal sales of children’s cosmetics; Smooth complaint channels, protect consumers’ rights and interests, and attach great importance to the complaints and reports that occur during the process of parents buying and children using children’s cosmetics, and dispose of them in time.

　　In Yao Jinju’s view, in view of the phenomenon of selling non-children cosmetics around schools, businesses should be given the obligation to pay attention or warn them according to law. At the same time, from the perspective of market supervision, we can rely on the "student safety regional system" to carry out supervision.

　　For example, the Regulations on the Safety Management of Kindergartens in Beijing Primary and Secondary Schools (Trial) stipulates that within 200 meters around the school, relevant departments should focus on rectifying the environmental order around the school according to their duties, and strengthen the supervision of business service places and business service activities around the school, as well as the public security situation and traffic order.

　　"In addition to strengthening supervision, citizens should also be encouraged to report illegal sales of non-children cosmetics or children’s cosmetics with unqualified quality around schools." Yao Jinju said.

　　What should parents pay attention to when choosing cosmetics for their children?

　　Zhang Bufeng believes that we should not blindly buy products marked with "food grade" and "edible", which are explicitly prohibited in the Regulations on the Supervision and Administration of Children’s Cosmetics. If consumers can’t identify whether cosmetics are children’s cosmetics, they should take the initiative to ask the operators, and can check the product registration or filing information through the "Cosmetics Supervision" App. Do not use beauty toys as children’s cosmetics.

　　Zhang Bufeng reminded that it is necessary to choose suitable cosmetics for children of different ages. According to the Classification Rules and Catalogue of Cosmetics issued by National Medical Products Administration, cosmetic efficacy claims used by infants aged 0-3 years do not include "make-up" categories such as beauty modification and makeup removal. To this end, parents should not buy "make-up" for infants under 3 years old. It is illegal to claim that the cosmetics label can be used by infants under 3 years old.

　　Yao Jinju said that "Xiaojindun" is not a product quality certification mark, and the label "Xiaojindun" on the cosmetics package only shows that this product belongs to children’s cosmetics, and its purpose is to "improve the recognition of children’s cosmetics and protect consumers’ right to know", which does not mean that the quality and safety of this product are certified. Therefore, in addition to paying attention to the "golden shield", parents should carefully check the business license of the operator, the national compulsory product certification certificate and other documents when purchasing, and choose a formal merchant with complete licenses to conduct transactions. At the same time, as consumers, we should pay attention to business information, product reputation, evidence retention and other matters.

　　The formation process of rainstorm is quite complicated. Generally speaking, the main physical conditions for rainstorm are sufficient and continuous water vapor, strong and lasting upward movement of airflow and instability of atmospheric structure.

　　The water vapor source of heavy rain in China comes from the southerly South China Sea and the Bay of Bengal, and from the western Pacific Ocean. In addition, rivers and lakes are also one of the water vapor sources. How does a large amount of water vapor rise to the sky and become cold and condense into raindrops? There are three situations that can make water vapor rise.

　

　　Sunlight causes water vapor to rise into clouds and cause rain.Under the strong solar radiation, the water surface is heated and evaporated, turning into invisible water vapor and entering the lower atmosphere. The lower atmosphere also rapidly increased thermal expansion and became lighter, and the hot and light air full of water vapor soared into the blue sky like "taking an elevator".

　　Water vapor rises on the front to form clouds and cause rain.Cold air forms an invisible "inclined staircase", which makes water vapor slide up into the upper atmosphere. Cold and warm air masses meet to form a front. Warm and light air rich in water vapor will slide or be lifted above cold and dry air, causing water vapor to rise and form thick clouds.

　　Water vapor is lifted into clouds on windward slopes to cause rain.If the warm and humid airflow moving horizontally from the water vapor-rich area is blocked by mountains, hills or plateaus, it will be forced to "climb" up the hillside and enter a higher place, thus forming clouds and causing rain on the windward slope.

(Editor: Liu Jia)

　　Cctv newsOn the 11th, US Secretary of State Tillerson arrived in Doha, Qatar, and continued to mediate the crisis of Qatar breaking diplomatic relations. On the same day, Qatar and the United States signed a memorandum of understanding on combating the financing of terrorism.

Qatar Foreign Minister Mohammed

　　On the same day, Qatar Foreign Minister Mohammed and Tillerson held a press conference. Muhammad said that the memorandum was signed within the framework of continuous cooperation between the two countries. Qatar and the United States discussed this memorandum for four weeks, which has no direct or indirect relationship with the crisis of breaking diplomatic relations. He called on the countries that broke diplomatic relations to join it.

　　US: The United States and Canada will share the responsibility for counter-terrorism.

US Secretary of State Tillerson

　　Tillerson said that the United States and Qatar will make more efforts to track funding sources, share information, strengthen cooperation and ensure regional security. He said that the United States and Qatar will share the responsibility and obligation of counter-terrorism.

Foreign ministers’ meeting of the four countries

　　On June 5, Saudi Arabia, the United Arab Emirates, Bahrain and Egypt announced that they had broken diplomatic relations with Qatar on the grounds of "supporting terrorism" and "undermining regional security" and imposed an embargo on Qatar. On June 23rd, the four countries handed over a 13-point request document aimed at resolving the crisis to Qatar through Kuwait. On July 5, the four countries issued a joint statement in Cairo, saying that Qatar’s response to the 13-point request was not satisfactory. In this regard, the Ministry of Foreign Affairs of Qatar expressed regret.

　　Tillerson began to visit many countries in the Middle East on the 10th to mediate the crisis of Qatar breaking diplomatic relations.

　　Saudi Arabia and other four countries: sanctions against cards will continue.

　　Saudi Arabia, the United Arab Emirates, Bahrain and Egypt issued a joint statement on the 11th in response to the signing of a memorandum of understanding between Qatar and the United States to combat the financing of terrorism, saying that the four countries will monitor whether Qatar fulfills the memorandum and the sanctions against Qatar will continue.

　　According to the statement, Qatar has failed to implement the Riyadh Agreement and its Supplementary Provisions in the past three years, and continues to support terrorist activities and interfere in other countries’ internal affairs. Therefore, Saudi Arabia and other four countries put forward 13 requirements to Qatar as a condition for solving the crisis of breaking off diplomatic relations.

　　The statement said that in view of Qatar’s non-compliance with the agreement, Saudi Arabia and other four countries believe that the signing of a memorandum of understanding between Qatar and the United States is not enough, and the sanctions imposed by the four countries on Qatar will continue until Qatar meets the requirements put forward by the four countries.

　　What about "red face" and "white face" singing together to mediate?

　　Since Qatar broke off diplomatic relations, the trend of the United States has been concerned by international public opinion. The storm of breaking off diplomatic relations occurred shortly after US President Trump visited Saudi Arabia. After the storm, Trump also repeatedly voiced his voice, which made it difficult for the United States to get rid of the suspicion of the initiator. After Saudi Arabia and other Arab countries put forward a series of conditions for the resumption of diplomatic relations to Qatar a few days ago, the relevant parties started intensive diplomatic interaction, and the United States, which was suspected of being the initiator, seemed to have begun to sing a "white face" and rushed to mediate. Why?

　　Will Tillerson’s visit bring a turning point to the long-stalled crisis of breaking off diplomatic relations in the Middle East?

　　After Qatar broke off diplomatic relations, although Kuwait and other countries tried to mediate, Germany, Britain and other foreign ministers went to the Middle East to mediate, the current situation has not made any progress. However, the US Secretary of State Tillerson’s visit is optimistic in Qatar, and Abdullah, editor-in-chief of one of Qatar’s largest newspapers, believes that Tillerson’s visit is crucial to the resolution of the crisis.

　　Abdullah said that the crisis of breaking diplomatic relations in the Middle East occurred after US President Trump visited Saudi Arabia, and Tillerson’s visit also meant that the United States hoped to solve the crisis of breaking diplomatic relations.

　　Regarding the future of the GCC, some analysts believe that the ongoing crisis and mutual accusations are likely to lead to the GCC falling apart. Abdullah believes that the mechanism of the GCC determines that Qatar will not be easily "kicked out" of the organization, and the crisis of breaking diplomatic relations will not last long.　　

　　Related reading

　　At the beginning of the storm of breaking off diplomatic relations, the US government expressed confusion

　　On June 5, four countries, including Saudi Arabia, announced that they had broken diplomatic relations with Qatar on the grounds of "supporting terrorism" and "undermining regional security", and imposed an embargo and blockade on Qatar. In this regard, many countries have called for the settlement of disputes through dialogue, while the attitude of the US government towards the Qatar issue is inconsistent and confusing.

　　On June 6, US President Trump sent three tweets on Twitter to express his position on "breaking off the storm". Two of them clearly expressed their support for Saudi Arabia and other countries to isolate Qatar.

　　But shortly thereafter, the State Council issued the opposite statement. US Secretary of State Tillerson called on all parties to handle conflicts through peaceful dialogue, saying that the United States is willing to play the role of mediator and promote reconciliation. US Defense Secretary Matisse also said that the relationship between the United States and the Gulf countries will not be affected, and cracking down on extremist organizations is the common goal of the United States and the Gulf countries.

US President Trump

　　Then on June 9, Trump once again publicly accused Qatar of "supporting terrorism for a long time".

　　Also on June 9, US Secretary of State Tillerson issued a statement calling on Saudi Arabia and other countries to immediately lift the "blockade" against Qatar and not to further escalate the situation.

　　In fact, this is not the first time that the attitude of the President of the United States is inconsistent with that of the State Council and the Ministry of National Defense. Some analysts believe that "a good COP and a bad COP" is a common means for various departments of the US government to face other countries.

　　At the beginning of July, after Saudi Arabia and other countries put forward the 13-point conditions for the resumption of diplomatic relations with Qatar, the relevant parties launched intensive diplomatic mediation interaction, and Trump’s attitude seemed to have changed &mdash; &mdash; When talking on the phone with Egyptian President Seyce, Trump stressed that all parties concerned should solve the problem through constructive consultation. Then, US Secretary of State Tillerson began his mediation trip in the Middle East.

　　At the same time, some analysts pointed out that the United States is willing to mediate because the United States is worried that the crisis of breaking off diplomatic relations will continue to affect the US military action against terrorism. In addition, Saudi Arabia and Qatar are important allies of the United States. Ending this diplomatic storm will also enable the United States to implement the arms deals reached with Saudi Arabia and Qatar respectively.

　　It is in the interest of the United States that many countries in the Middle East are "split and continuous"

　　Observers believe that this move by the United States not only has the intention of stopping when it is good, but also has the consideration of preventing the storm of breaking diplomatic relations from further fermenting, thus damaging the interests of the United States &mdash; &mdash; The constant contradictions and mutual suspicions among Arab countries in the Gulf are obviously conducive to the United States’ intervention in Gulf affairs, but the complete break-up of these countries will give Iran an opportunity and even reap profits, which the United States does not want to see. Therefore, it is in the best interests of the United States to "split and continue" among the Arab countries in the Gulf.

Text, picture/Guo Qi Jiao Xueke

In the wind, in the rain, they used Dai Yue’s maritime patrols again and again, day and night, tackling difficulties and fighting in the maritime defense line in Shenzhen; Weave a secret anti-fraud protection network to protect the citizens’ "money bags". They take the iron and blood of others as their responsibility, care about the safety and warmth of the people, and write a loyal heart for the people; Regardless of the reasons for losing contact, the length of time, men and women, old and young, and the nationality of the personnel, we will check the newspaper immediately and respond to every request, and check it out with the fastest response, the most urgent state and the most complete resources, effectively eliminating the troubles of people getting lost, losing contact and being separated … This fact of safeguarding one party’s peace and escorting social peace and harmony has warmed people’s hearts, gathered people’s hearts and strengthened their confidence.

In recent years, Shenzhen Baoan Public Security Bureau has persistently cracked down on all kinds of outstanding crimes, made efforts to solve the people’s "urgent difficulties and worries", and constantly enhanced their sense of gain, happiness and security. Social security continued to improve, and "Peace and Baoan" reached a new level.

In the coastal defense line in the western waters of Shenzhen, there are such a group of people who step in the wind and check the passing ships every day; Bravely shoulder heavy burdens and guard against all kinds of sea-related crimes; Carry out propaganda of popularizing law with intention. They are Baoan public security coastal defense police.

Every day, 10 coastal police stations and streets in Baoan Public Security Area are based on more than 60 duty points along the coast, and more than 400 full-time coastal defense forces are on patrol to defend Shenzhen’s "West Gate".

According to reports, Baoan Public Security has always maintained a clear understanding and high vigilance in building a defense line and holding the pass, constantly consolidating the foundation of prevention and control and building four defense lines. The first line of defense: set up more than 60 duty booths, and arrange personnel to patrol full-time 24 hours a day. The second line of defense: set up barbed wire, radar photoelectric system, searchlights and other equipment along the coast to achieve full coverage of the coastline. The third line of defense: a floating ball is set every 2-3 meters, which is connected in series with fiber steel ropes and fixed by an anchor every 25 meters. It has been erected for 48.1 kilometers to prevent ships from landing. The fourth line of defense: a number of duty boats are dispatched to patrol offshore every day.

"We are Shenzhen Public Security Bureau, and we will conduct routine inspection. Please stop the ship!" At 11 o’clock on the morning of March 11, the coastal defense smuggling police of Shajing police station watched the patrol boat and shouted to the passing sand carrier in the waters under their jurisdiction. After boarding the ship, Guan Ming carefully checked the health codes of the people on board and the relevant documents of the ship’s operation. "Thank you for your cooperation. Be sure to pay attention to safety and wish you a safe journey."

Every day, Guan Ming and his colleagues drive patrol boats, patrol back and forth in the waters under his jurisdiction, check passing ships and guard against all kinds of sea-related crimes. Because criminals often engage in illegal and criminal activities such as smuggling and smuggling at night, according to this feature, the Shajing police station started the normal patrol control on the sea surface early, and set up eight checkpoints in the waters under its jurisdiction.

"We patrol the sea. In addition to cracking down on illegal and criminal activities, it is also one of our duties to inspect passing ships and carry out legal publicity. We will sign a letter of commitment with the person in charge of the ship not to participate in illegal and criminal activities." Yan Weilong, a policeman from Fuhai Police Station of Baoan Branch, said.

In view of the key parts and weak links of coastal defense, Baoan Public Security vigorously implemented six management measures to plug the loopholes. First, by means of boarding collection and video presentation, the ship was fully controlled, and the ship-related elements were fully collected. 566 ships have been verified, and 2,720 people have collected information, preached legal knowledge and signed a letter of commitment. Second, for key wharves with potential safety hazards, "one wharf and one special class" will be implemented, led by the Political and Legal Committee of the District Committee, and the departments of streets, public security, maritime affairs, law enforcement and health care will jointly carry out rectification work, strengthen the "three defenses" facilities in nine vulnerable areas, and set up 24-hour full-time inspection at the loading point, import and export of the wharf. The third is to organize 41 enterprises along the route to establish a linkage mechanism. Fourth, the joint maritime and marine police departments dispatched two large duty ships to anchor in the offshore. Fifth, joint street and dock management should check and control the ashore personnel of operating vessels according to those who return to the depths in key epidemic areas to prevent stowaways from landing. Sixth, improve the construction of civil air defense, physical defense and technical defense along the coastal defense in the whole region, sign letters of responsibility with 7 streets and 41 enterprises along the line, and compact the main responsibility of management.

Since the beginning of this year, Bao ‘an Public Security Bureau has played the role of a professional police in accordance with the spirit of the instructions of the superior, "Don’t leak a word, don’t miss a moment, and check it to the end", in order to carry out a full chain attack. Eight smuggling cases have been cracked, 30 people have been arrested, 18 people have taken criminal compulsory measures, 17 ships with "three noes" have been seized, and 272.794 tons of frozen products have been seized. In addition, it also coordinated the establishment of a special reward fund in the whole region to reward those who report illegal immigrants and meritorious personnel quickly and create a good atmosphere for the people to participate in the "double opposition" work.

Anti-fraud early warning and dissuasion work is not only a race against time, but also a scientific and technological contest.

At 11 o’clock on April 23, Fuyong police station received an early warning interception instruction issued by the anti-fraud center of Baoan Branch, saying that Ms. Zeng, a resident of Fuyong Street in Baoan District, had been talking to an overseas number for 20 minutes, which may have been deeply brainwashed by fraudsters and needed to be intercepted at home immediately. After receiving the instruction, Fuyong police station immediately arranged the blue vest police force to come to the door to implement early warning and dissuasion. At this time, the victim, Ms. Zeng, locked herself in the room and refused to open the door anyway.

Discourage interception is imminent! The police knocked on the door of Ms. Zeng’s room and loudly dissuaded her. Just when the police almost broke into the house, Ms. Zeng opened the door. At this time, she was holding a mobile phone with a blank face. Fortunately, under the rapid response of the police, Ms. Zeng’s operation of entering the bank card password was stopped in time. After verification and confirmation, nearly 1.5 million deposits in Ms. Zeng’s card have not been transferred away, and everyone present finally breathed a sigh of relief.

After investigation, the victim, Ms. Zeng, had just been defrauded by impersonating the "Public Prosecution Law". The liar lied that she was involved in a money laundering case. In order to "cooperate with the investigation", she installed the video conference APP under the guidance of the liar and revealed the bank card account number. When she was about to enter the password on the screen, the police rushed to dissuade her. Afterwards, Ms. Zeng and her wife, who were in shock, listened to the police’s explanation and education on related fraud cases and techniques in detail, only then did they realize that their hard-earned money was almost destroyed, and they constantly thanked the police for their help.

It is reported that since the beginning of this year, Baoan Public Security has taken the "three-level linkage" as the starting point, continuously optimized the early warning and dissuasion mechanism, and upgraded the "emergency stop protection mechanism" through linkage with the three major operators, integrating scientific and technological means such as early warning data, big data and artificial intelligence with early warning prevention and management, and other innovative practices, fully pushing the early warning and dissuasion with Baoan characteristics, and fully building a "firewall" to prevent people from being cheated. Since the beginning of this year, a total of 341,650 early warning data have been processed, 39,649 visits have been made, 26,680 people have been dissuaded, 1,250 cases have been successfully intercepted, with losses exceeding 35 million yuan, 2,478 cases have been stopped urgently, and the amount of payment stopped has reached 115.4 million yuan, effectively guarding the people’s "money bag". The effectiveness of early warning and dissuasion in the first quarter is far ahead in the city. At the same time, Baoan Public Security actively countered by upgrading and optimizing interception, and through fund analysis and the original road return mechanism, 269 transactions totaling RMB 8.382 million have been successfully returned to the defrauded Baoan District residents in time this year.

At the beginning of this year, in view of the frequent cases involving ETC fraud, the shenzhen public Criminal Police Detachment and Baoan Branch set up a task force. Through the series and parallel arrangement and the study of capital flow, it was found that although the cases involved were seemingly unrelated, the modus operandi of the cases was similar, and there was a great possibility that the whole chain of professional gangs controlled the operation.

This clue happens to be an opportunity for a new type of telecommunication network fraud criminal gang to show its "fox tail" rarely. In order to seize the fighter plane and deeply understand the operation details of the gang, the task force took the lead in collecting the net from the gang members who participated in the direct operation of the POS machine. On January 6, 2022, the police of the task force quickly captured three suspects, including Zhou, in Shenzhen. Through interrogation and investigation, on January 27, 2022, the task force arrested four suspects, including Zhang, who was on the line in this case, and seized a number of crime tools such as mobile phones, POS cash boxes and laptops on the spot, successfully winning a working group within the criminal gang.

Through in-depth investigation by the task force, a professional telecommunication network fraud gang with clear division of labor and organizational discipline has gradually surfaced, involving domestic and overseas joint operations, multiple domestic groups distributed all over the country to steal brushes, and involving victims and suspects all over the country. After accurately grasping the important information such as the gang’s organizational structure, division of responsibilities and modus operandi, on February 24, 2022, the task force made another thunderous attack, continuously moving around the country to carry out large-scale unified operations, and arrested 16 criminal gang members involved in operating the phishing website backstage, money laundering, system development, drainage, buying and selling financial accounts and stealing brushes. On April 11, 2022, Baoan Public Security finally persuaded the overseas leader of the gang to return to China, and arrested and returned to Shenzhen after completing the isolation.

Anti-fraud work adheres to the principle of "thinking is not loose, standards are not lowered, and strength is not reduced". After cracking the ETC fraud case, Baoan Public Security Bureau has organized a total of 50 full-time police officers to take part in two rounds of special attacks. At the same time, based on the local situation, it keeps a close eye on the clues of "broken cards", summarizes the characteristics of such cases, and successively destroys three criminal gangs involved in fraud. As of the third week of April, 767 fraud-related criminal cases were solved in the whole region, up by 36.48% year-on-year, and 309 suspects were arrested. Bao ‘an Public Security has continuously rallied the whole police to crack down on telecommunication network fraud through continuous heavy punches, and acted pragmatically with practical actions, thus effectively deterring fraud-related crimes.

My son Xiao Li left home to work hard in the south. In the blink of an eye, there was no news in the past two years, which worried her mother Ms. Zhao. In desperation, Ms. Zhao, who is far away in Shanxi, called the Shangnan Police Station of shenzhen public Baoan Branch for help. Xie Chenghui, a policeman, and Luo Zhijun, an auxiliary police officer, launched an emergency tracing operation through some clues provided by Ms. Zhao. After expanding the search scope, the police finally found the news of Xiao Li at the end of February this year. "We found that Xiao Li often hangs out near an Internet cafe on Shangnan Street in Baoan District." Xie Chenghui said.

After learning this clue, the police quickly contacted Ms. Zhao to tell the good news. Ms. Zhao was so surprised that she came to Shenzhen from her hometown in Shanxi at the first time. In order to find Xiao Li as soon as possible, the police and Zhao Nvshi carefully investigated and visited Shangnan Street for 2 consecutive days.

Where there’s a will, there’s a way. At about 11 pm on March 4, Xiao Li appeared at the entrance of an Internet cafe on Shangnan Street in Baoan District. Seeing that her son was safe and sound, Ms. Zhao wept with joy and thanked the police constantly. "Thank you, police comrades, for bringing my son back to me." Seeing that they finally got together and set foot on their way home safely, everyone involved in this tracing operation felt warm.

Behind the lost cases are vivid lives, which affect families in a hurry. As the largest immigrant city in China, Shenzhen has a large foreign population and great mobility, and the elderly and children are easily lost and separated because they are not familiar with the urban environment. According to the relevant deployment of the Municipal Bureau, Shenzhen Baoan Public Security Bureau adheres to the principle of "people first, life first" and establishes a service center for the lost persons in the sub-bureau, with the fastest response, the most urgent state and the most complete resources. Since the beginning of this year, a total of 4,317 people who lost contact have been found, with a success rate of 99.2%, effectively eliminating the troubles of people getting lost and lost.

Fully involved, fully accepted, and show the "true color" of serving the people with actions. In the face of seeking help for people who have lost contact, Baoan Public Security Bureau insists on "checking immediately after receiving the report, giving whatever is needed", preferring "looking for nine holidays in ten times" and never "missing one person", completely changing the problems of the people who have lost contact for help, slow response, low efficiency in finding people and long period, so that the old saying "looking for the police in danger" can be effectively transformed into a sense of security and gain for the citizens.

Synthetic operations, joint search, and efficiency to measure the "quality" of tracing services. The efficiency of finding the missing persons is the most concerned issue of the masses, and it is also the professional ability that the public security organs must constantly improve. Shenzhen Baoan Public Security focuses on the problems of insufficient grass-roots resources, fragmented work and difficulty in finding people in the traditional process of finding people, makes full use of the advantages of public security big data, binds the search center for missing persons with the synthetic warfare center, and integrates the resources of command, criminal investigation, network police, traffic police, legal system and other departments to be on duty around the clock, so as to increase manpower and resources in handling cases, which greatly improves the efficiency of finding missing persons.

Compacting Responsibility and Closed-loop Relay —— Taking "finding" as the "end point" of tracing service. Finding people is the simplest expectation of the masses. Bao’ an Public Security never abandons or gives up every case of losing contact for help, regardless of the length of filing and the length of missing time. It clarifies the closed-loop operation mechanism of "receiving police-marking-finding-closing-feedback" and tightens the responsibility chain for following up the whole process of each case of "finding someone". Major sensitive lost contact police cases are marked by the main leaders and questioned all the time. Generally, the lost contact police cases are marked by the leaders in charge and followed up in real time. We made every effort to tackle the historical backlog of the stock of lost children, and launched a green channel for collecting DNA nearby to compare and find relatives, successfully helping many separated families to have a dream reunion.

CCTV News:On the afternoon of January 18th, the Ministry of Commerce held a regular press conference. According to the spokesperson, the "2024 National Online New Year Festival" kicked off on January 18 and the event will last until February 17.

According to the Ministry of Commerce, digital, healthy and green are the new trends of consumption, and they are also the main new ideas of local activities. Around digital consumption, Beijing and other places held the first show of computer, communication and consumer electronic products, the "Science and Technology New Year Festival" and other activities. Around healthy consumption, Shanghai and other places hold "super holidays" and other activities in response to the seasonal demand in winter. Around green consumption, all localities have guided e-commerce enterprises to strengthen the supply of "small dishes", issued green packaging initiatives, and advocated a green and environmentally friendly lifestyle.

He Yadong, spokesman of the Ministry of Commerce:Closely following the needs of the New Year Festival, we will carry out three major "Spring Festival Rejuvenation" promotional activities. Around the rejuvenation of the home, Tianjin and other places carried out activities such as live broadcast of furniture and home appliances and special sales subsidies. Around the rejuvenation of the national tide, Zhejiang and other places carried out activities such as the "Non-legacy New Year Festival" and launched more domestic "tidal products". Around the scene rejuvenation, Shaanxi and other places carried out activities such as "Night Chang ‘an Chao Chang ‘an" to enhance the consumer experience in all aspects.

National Development and Reform Commission: Launching the "Consumer Help for the Spring Festival Action" in 2024

The National Development and Reform Commission (NDRC) recently launched the "Consumer Assistance for the New Year Action" in 2024, mobilizing and calling on organs at all levels, enterprises and institutions, social organizations and the general public to actively participate in holiday consumption assistance, and actively purchasing various products and cultural tourism services in underdeveloped areas such as poverty-stricken areas under the premise of fully respecting market rules.

In 2024, in the "Action of Consumption Helping the Spring Festival", all relevant regions and departments should increase the consumption and purchase of characteristic agricultural products in underdeveloped areas such as poverty-stricken areas, encourage them to go to poverty-stricken areas to carry out county-level cultural tourism consumption, and continue to strengthen the sales and assistance of products and services in poverty-stricken areas, especially in "three districts and three States", key counties for national rural revitalization, and relocation and resettlement areas.

Do a good job in organizing the supply of characteristic agricultural products in underdeveloped areas, smooth the passage from mountain to city, strengthen the control of product quality, and further increase the proportion of market-oriented help and sales.

In 2022 and 2023, in the "Consumer Help the Spring Festival Action", the total amount of sales assistance from various regions and departments reached 170 billion yuan, which effectively improved the income level of people out of poverty, promoted the development of characteristic industries and product upgrading in underdeveloped areas, and promoted the sustained recovery and expansion of domestic consumption.

Ministry of Culture and Tourism: Carry out the cultural tourism activities of "Happy New Year" throughout the country.

The reporter learned from the Ministry of Culture and Tourism on January 18th that during the Spring Festival, the Ministry of Culture and Tourism will organize the theme cultural and tourism activities of "Happy New Year" in 2024. The activities cover many fields such as Huimin’s cultural performances, intangible experience display, tourism and leisure consumption, and enrich people’s holiday life.

It is understood that the theme culture and tourism activities of the 2024 Spring Festival of "Happy New Year" were carried out from January 18 to March 11. This activity covers many fields such as public service activities, non-legacy experience display, tourism and leisure consumption, ice and snow research and tourism.

The theme activity of "Colorful Study Tour to China" is jointly participated by 11 provinces including Yunnan, Shandong, Zhejiang, Anhui and Jiangxi. Yunnan will launch a series of research activities such as "exploring biodiversity"; Jiangxi will launch the activity of "Traveling with Poetry in Jiangxi"; Protecting the beautiful Yangtze River theme research tourism activities, with the participation of provinces along the main stream of the Yangtze River; Shanghai will launch a "century-old civilization, butterfly changes into a new life &mdash; &mdash; Industrial research opens the next wonderful event; Hubei will launch a series of research theme activities such as "telling the epic of the red soul" and "welcoming the New Year without leaving behind"; The "ice and snow theme research tourism activities" are mainly concentrated in Heilongjiang and Jilin.

In addition, during the Spring Festival, the Ministry of Culture and Tourism will also launch the "100 Cities and 100 Districts" financial support consumption action plan, covering the whole chain of "eating, living, traveling, buying and entertaining", so that people can benefit and enterprises can really benefit.

　　February 4th is the 17th World Cancer Day, and this year’s theme is "WE CAN, I CAN". The member of the Standing Committee of Cancer Radiotherapy Committee of China Anti-Cancer Association and the president of Cancer Hospital said: At present, 70% of cancer patients in our city are in the middle and late stage when they are diagnosed, so it may be a better choice for them to eliminate the fear of cancer and realize coexistence with cancer.

　　70% of cancer patients need to live with tumors.

　　Mr. Luo, who lives in Yubei District, is 55 years old. He is used to working from nine to five every day. If no one tells him, no one will think that he is actually a cancer patient. Five years ago, he suddenly felt that he was always urinating, but he couldn’t urinate. At first, he thought he was getting angry. But a pile of heat-clearing drugs didn’t improve after eating, and the more urgent the urine, the less smooth it was, and sometimes it was accompanied by pain. At this time, he thought about going to the hospital for examination.

　　I didn’t want to be diagnosed with prostate cancer and have bone metastasis. I have lost the best opportunity for surgery and can only use antiandrogen drugs to control my condition. In the face of cancer, he did not intend to give up, but actively cooperated with the treatment. After one year, his condition gradually stabilized, and Mr. Luo began to plan to go to work in the unit.

　　Professor Dean of the Municipal Cancer Hospital said that according to the "2015 China Cancer Statistics" issued by the National Cancer Center, there were 4.3 million new cancer cases in China in 2015, and the number of cancer deaths exceeded 2.8 million; In Chongqing, there were about 80,000 new tumors and more than 50,000 cancer deaths in 2014. Because the incidence of tumor is relatively concealed, more than 70% of cancers are found in the middle and late stages, and the best opportunity for surgical treatment is lost. For them, survival with tumor may be a better choice.

　　Unfortunately, in real life, there are not many patients who can scientifically understand the survival with tumors like Mr. Luo. As soon as many patients heard that they could not operate, their spirits suddenly collapsed and they thought they were hopeless. In fact, surgical treatment is not the only treatment for all tumors; Even if we miss the best opportunity for surgical treatment, it doesn’t mean that there is no cure. At present, tumor treatment advocates comprehensive treatment, which includes surgery, chemotherapy, radiotherapy, endocrine therapy, traditional Chinese medicine treatment and other ways. Experienced specialists will choose the appropriate treatment according to the results of tumor pathological examination, course of disease and development trend.

　　"It is very important for cancer patients and their families to accept" survival with tumor ",which is a more pragmatic method for treating advanced cancer." Dean said that cancer is essentially a genetic disease, and all cancers come from genetic mutation, which is caused by genetic mutation and epigenetic regulation. At present, human beings can’t use drugs to reverse this genetic mutation and "kill all cancer cells" in the body.

　　It is also a pragmatic choice for patients in the middle and late stage to realize long-term "survival with tumor" and "peaceful coexistence" with tumor. Everyone should treat it as a medical disease with disease, and treat tumor as a chronic disease such as hypertension, diabetes and coronary heart disease, which is more conducive to treatment.

　　The misunderstanding of survival with tumor needs to be vigilant

　　There may be many people who don’t understand that living with a tumor is not cured. There is a tumor in the body, and the condition may deteriorate at any time. Can this be safe? Dean Wu Yongzhong said that in fact, survival with tumor is not to let it go, but to choose a suitable treatment model, which is also the core of "individual medicine" developed from "evidence-based medicine" in recent years. First of all, we should recognize the fact that the dream of conquering tumor has not been realized.

　　WHO has regarded tumor as a chronic disease, because its condition has a process of development, which can not be cured and exists for life, just like diabetes, hypertension and coronary heart disease. Secondly, sometimes over-active treatment is also a kind of injury. In clinic, some elderly cancer patients are often encountered. When children hear that they can have surgery and treat at all costs, they have not achieved good results. This is because the elderly, especially those over 80 years old, have degraded their physical functions and cannot tolerate surgery and chemotherapy at all.

　　At this time, you don’t have to think about eliminating the tumor at all. You can choose radiotherapy alone or other treatments, so as to survive with cancer. Advocating survival with tumor again also means waiting for treatment conservatively. If it can be cured by surgical resection, radiotherapy and other treatment methods, tumor patients should still be encouraged to actively treat.

　　Age-related macular degeneration (AMD) mostly occurs in people over the age of 50, and it is one of the main blinding diseases of the elderly in the world. According to statistics in 2010, there are more than 23 million AMD patients worldwide. The patient’s chief complaint is decreased vision, which is characterized by the absence of central visual field (see schematic diagram).

　　Normal visual field (left), central visual field damage caused by AMD (right)

　　Age-related macular degeneration can be divided into Dry AMD and Wet AMD. Dry amd is characterized by no vascular proliferation, while wet amd is characterized by obvious vascular proliferation in macular area. There is almost no treatment for dry age-related macular degeneration, while wet age-related macular degeneration is mainly aimed at vascular proliferation. For vascular proliferation, Genentech’s Ranibizumab (trade name: Lucentis) is a fragment antibody against VEGFA, and it costs two thousand dollars for a shot. However, many places bypass Ranibizumab and choose Avastin (Avastin), which is also anti-VEGF, for only fifty dollars. It can be seen that there are policies and countermeasures, which are available to people at all times and all over the world, but the interests are accelerating. In addition, laser therapy is also aimed at vascular proliferation. Although there is symptomatic treatment for vascular hyperplasia, it is also a temporary solution, because macular degeneration itself has not improved.

　　A core problem of macular degeneration is degeneration of retinal pigment epithelial cells (RPE). These cells are close to the interlayer between Choroid and optic nerve cells in retina, and are responsible for bringing blood nutrition to optic nerve cells. If this layer of cells degenerates, the optic nerve cells will not get nutrition, so the vision will decrease. There’s an old saying in China, what can I do without fur? Is the image explanation of this disease.

　　A remarkable pathological feature of macular degeneration is yellow sediment distributed on the retina, which is a mixture of protein and lipid, but its source is unknown, and it may be an inflammatory product, and its pathological function is to destroy retinal pigment epithelial cells (RPE). See the figure below.

　　Since it is a degenerative disease, the research and development of drugs lacks molecular targets, which are a bit like Alzheimer’s disease and neurodegeneration, and there are not many effective targets. In contrast, the stem cell technology that surfaced in the past ten years is an ideal choice. Stem cells are induced to differentiate into retinal pigment epithelial cells (RPE), which provides a feasible and effective method for the treatment of macular degeneration.

　　Can normal retina replace diseased retina? A few decades ago, someone replaced the diseased retina with the baby’s retina (of course, the source was the baby who died in a car accident under two years old), and the success rate was very low, because the source of newborn retina was difficult, the protection was difficult, and the operation was difficult, which were all restrictive factors. However, some people have gained some vision (such as light perception and figure) through retinal replacement. This scheme can at least prove that infant retinal replacement is a direction that can be improved. However, it is not successful to replace the bad eye retina with the good eye retina of the same adult, which shows that the physiological age of retina is an important reason. Nowadays, retinal pigment epithelial cells (RPE) can be produced from stem cells, whether from embryonic sources (hESC) or from self-induced sources (iPSC), and they can be made into Sheet, which is beneficial to surgical implantation. Of course, there are many technical problems, mainly the problem of eye surgery and the problem of ensuring the survival of cells after implantation. A positive factor is that the eye is an immune escape, so don’t use immunosuppressants, immune rejection should be small, which is conducive to survival.

　　Regenerative medicine is a new field, and big pharmaceutical companies are unwilling to take this risk. Seven years ago, the author worked in the world’s largest ophthalmic pharmaceutical company (Allergan) and once recommended this project, but the decision makers are interested in Miu Miu. At present, several small companies have pushed the application of regenerative medicine in senile macular degeneration into the clinical stage. Although I dare not predict when it will be approved by the FDA, it is still expected as a promising direction. After all, there is no other way at present. Although the experiment of regenerative medicine is still in the "primary stage of socialism", the AMD market is very large, and there are still some large and medium-sized pharmaceutical companies to follow up. Not long ago, Astra, the second largest pharmaceutical company in Japan, bought Ocata Therapeutics LLC to jointly develop this method for treating AMD, which mainly focuses on hESC inducing retinal pigment epithelial cells (RPE).

　　Regenerative medicine is not only dedicated to age-related degenerative macular degeneration (AMD), but also can be used to treat another cause of blindness, Retinal pigmentosa. It also damages retinal pigment epithelial cells (RPE), but retinal pigment degeneration damages peripheral visual field, and other eye diseases such as glaucoma and corneal burn. In order to give you a big picture of regenerative medicine in treating ophthalmic diseases, the author summarizes the general situation of some companies entering clinical trials at present. I sincerely hope that these companies can succeed in regenerative medicine and bring good news to patients with ophthalmic diseases.

　　Table 1. Summary of Clinical Trials of Regenerative Medicine in Treating Ophthalmic Diseases

In the luxury camp of the automobile industry, Audi has always occupied a place with its unique design and excellent performance. With the wonderful appearance of the new generation Audi A5L, we can see another bold attempt of Audi in the luxury mid-size car market. This is not only a simple product update, but also a profound insight and accurate layout of Audi’s luxury car market in the future.

Let’s start with the design.

The new Audi A5L inherits the design language of Audi family, but on this basis, it pays more attention to showing the sense of movement, and at the same time, it also presents the characteristics of youthfulness.

The front face of the car adopts a more sporty honeycomb air intake net, and the long and narrow matrix lights on both sides make the whole car look more aggressive.

The embellishment of the side of the car body, semi-hidden door handles and red brake calipers not only enhances the sense of technology, but also adds a sporty atmosphere.

The design of the frameless door is a highlight of the coupe, which is beautiful and full of movement.

In terms of size, the length of the new Audi A5L has increased to 4902mm and the wheelbase has been extended to 2,965 mm.. Compared with competing products, it has obvious advantages. After such changes, the new Audi A5L is more conspicuous in the length of the car body and the internal space, bringing passengers a more spacious and comfortable feeling.

This size not only leads in data, but also brings consumers a great luxury experience in sense.

In the rear part, the new car has been upgraded to a penetrating taillight group. The application of the second generation digital OLED technology provides 8 kinds of personalized signature light signs, and the display effect is fantastic.

In terms of interiors, the new Audi A5L also spared no effort. The floating curved double screen, the entertainment screen on the front side of the co-driver, and the brand-new double-flat-bottomed touch steering wheel all make the sports elements burst. The decoration of black piano paint further enhances the texture of the car. In terms of intelligent driving, the new car matches the L2++ level unmanned intelligent driving assistance system, which shows Audi’s in-depth exploration in the field of intelligence.

In terms of power, the new A5L is equipped with the fifth-generation EA8882.0TFSI engine, and comes standard with a 48V light mixing system, which is divided into high and low power adjustment versions, and is also equipped with a quattro four-wheel drive system. This power combination not only ensures the smoothness of daily driving, but also satisfies consumers’ pursuit of driving pleasure.

The new Audi A5L is officially unveiled. It is the successor and the new strategy of Audi brand in the field of luxury medium-sized cars. This car strives to attract consumers’ attention through more luxurious configuration, more spacious and comfortable space and more advanced technology. For young users, this car is likely to become their first choice, mainly because of its unique design, outstanding brand influence and strong product strength.

Generally speaking, the new Audi A5L has added new advantages for Audi to compete in the luxury mid-size car market with its unique design, exquisite interior, strong power and leading technology configuration. It shows Audi’s profound understanding of the future luxury car market, and also embodies the brand’s spirit of pursuing innovation and breakthrough. After the official listing in 2025, the new Audi A5L will become an important highlight of the luxury car market. With these characteristics, the new Audi A5L has emerged in the market and consolidated the brand image of Audi. With excellent design concept and advanced technology, this model will surely attract the attention of many consumers. At the same time, Audi continues to invest in R&D and innovation to ensure that each model can meet or even exceed customer expectations. Therefore, when the new Audi A5L is unveiled in 2025, it will undoubtedly become a bright star in the luxury car field.