Original Guo Lin Ji Lianmei Ji Lianmei Pharmacist

Everyone should have seen the hot search this morning about the death of 28 people in South Korea after being vaccinated with influenza vaccine, which made many friends worry about the safety of influenza vaccine.

I probably followed the news. At present, I suspect that two cases are related to anaphylactic shock. The relationship between other deaths and influenza vaccine has not been established and is still under investigation.

It is said that the death toll rose to 36 in the afternoon, but South Korea did not stop the flu vaccination. It is likely that the death has nothing to do with the vaccine. This incident is unusual, and I will continue to pay attention to the progress of this incident.

With regard to these two deaths suspected of anaphylactic shock, let me popularize the knowledge of adverse reactions related to influenza vaccine.

Vaccines are medicines, and adverse reactions may occur when any medicine is used. Anaphylactic shock is a rare adverse reaction that may occur when any vaccine is inoculated.

Moreover, whether to treat diseases or prevent diseases, whether to use drugs or not is a choice after repeatedly weighing risks and benefits.

As far as influenza vaccine is concerned, it is a relatively mature drug. If its adverse reactions are weighed against the risk of serious complications after getting the flu, the advantages of influenza vaccination must outweigh the disadvantages. Therefore, mainstream medical views have always recommended that everyone get the flu vaccine, and I personally recommend it, and I have always adhered to the relevant knowledge of popular science influenza vaccine.

There are three types of influenza vaccines this year, namely inactivated trivalent influenza vaccine and tetravalent influenza vaccine by intramuscular injection, and attenuated trivalent influenza vaccine by nasal spray.

Below, we will talk about their common adverse reactions respectively.

First, inactivated influenza vaccine (including trivalent and tetravalent)

The common side effects of inactivated influenza vaccine by intramuscular injection are mainly manifested in two types:

Local reaction, that is, swelling, induration, pain, burning sensation at the inoculation site, etc.

Systemic reactions, namely fever, headache, dizziness, lethargy, fatigue, myalgia, general malaise, nausea, vomiting, abdominal pain, diarrhea, allergies, etc.

These side effects have two characteristics:

First, it is usually mild, with few severe reactions.

Second, it can fade by itself within a few days.

In order to look more intuitive, we summarize these common side effects and their countermeasures as follows:

Two, freeze-dried nasal spray influenza attenuated trivalent vaccine

In this year (2020), freeze-dried live attenuated nasal spray influenza vaccine was newly launched in China. During the phase III clinical trial of the vaccine, 4,500 subjects aged 3-17 were vaccinated once, and the safety was observed for more than 6 months after vaccination. The results are as follows:

From the data point of view, the overall safety of this vaccine is good. The safety data of similar products abroad are similar, with mild adverse reactions and self-healing. Serious adverse reactions are rare.

However, because the vaccine has just been applied in China this year, the biggest challenge for vaccinators and recipients is unfamiliarity, so both sides need to strictly grasp the contraindications of attenuated nasal spray vaccine, so as to avoid predictable adverse reactions.

For example, although there is a needle in the vaccine box, this needle is used to prepare lyophilized powder for dissolving the vaccine, and the final vaccine is inoculated by "nasal spray". If the vaccinator is negligent and takes it for granted that he can inject with an injection needle, it will bring harm to the vaccinator.

For example, if the vaccinator has rhinitis or asthma, he can’t use the nasal spray live vaccine, because the nasal mucosa congestion and swelling caused by rhinitis may weaken the effect of the vaccine, and the rhinitis that may occur after vaccination may also be confused with the original rhinitis. It is also not suitable for children who are regularly receiving nasal spray treatment.

Another example is that the vaccine is a live vaccine, which is not suitable for children with impaired immune function, because it may theoretically cause children with impaired immune function to contract the flu. However, children with impaired immune function can be safely vaccinated with inactivated influenza vaccine.

After vaccination, you need to observe in the immune unit for 30 minutes to ensure that there is no serious allergic reaction before leaving.

Finally, I would like to reiterate my view on influenza vaccine: it is a relatively mature drug. If we weigh its adverse reactions with the risk of serious complications after getting the flu, the advantages of influenza vaccine must outweigh the disadvantages.

I hope everyone will not give up eating because of choking.

I also recorded a short video of related knowledge, which will be posted on the video number tomorrow. Welcome to identify the QR code below and pay attention to my video number.

If the dry goods explained in the video are helpful to you, please help me share them with more parents. Every praise, forwarding and comment from you is the motivation for me to keep updating the video number. Thank you for your support!

People who like this content also like it.

Original title: Common Adverse Reactions of Influenza Vaccine and Countermeasures

Read the original text

　　[car home Information] The new model 2.4LX of Guangzhou Honda’s eighth-generation Accord went on sale today.Pricing is 219,800 yuan.Enjoy the warranty policy of "three years or 100,000 kilometers for the whole vehicle". At present, the car in Beijing has arrived at the store and fully accepted the reservation.

　　The launch of the new eight-generation Accord 2.4LX enriches the Accord’s product line, reducing the price range of the 2.4L model by another 10,000 yuan, and the price of 219,800 yuan is the same as the top model of the Accord 2.0L. Appearance, the new model has not changed, only some configurations have been adjusted.

　　Compared with the original Accord 2.4L, the 2.4LX model has three reductions, namely, xenon headlights are cancelled, halogen bulbs are used instead, headlight cleaning device is cancelled, and the rear seat air outlet is reduced.

　　In 2008, the Eight-Generation Accord sold a total of 170,517 vehicles, ranking first in the medium-sized car market. The launch of the new model has enhanced the fighting capacity of the Eight-Generation Accord in the auto market in 2009. Although some of the reduction has reduced some luxury feelings, the decline in the price is the most affordable for consumers.

　● Manufacturer information

　　On January 12, 2009, Guangzhou Honda Automobile Co., Ltd. announced that it would launch a brand-new model 2.4 LX of the eighth generation Accord sedan, with the manufacturer’s guide price of 219,800 yuan, and enjoy the warranty policy of "three years or 100,000 kilometers for the whole vehicle". It is understood that this new car has arrived in Guangzhou Honda national special sales service store one after another, and fully accepted the reservation, adding another fire to the auto market on the eve of the Spring Festival.

　　Experts in the industry commented that just after New Year’s Day in 2009, the eighth generation Accord took the lead and fired the "first shot" in the medium-sized car market, which not only showed its confidence in defending the 2009 sales champion, but also predicted that the competition in the automobile market this year will be more intense and more exciting.

● Perfect start, consolidating the leading position in the 2.4L market segment.

　　As the "opening work" of the eighth-generation Accord sedan in 2009, the eighth-generation Accord 2.4LX continues to adhere to the concept of "B++".In terms of body size, the length, width and height reach 4945×1845×1480mm and the wheelbase reaches 2800mm respectively. The size and space are beyond all models in the same class, which well meets the customer’s requirements for space and comfort. The interior design fully shows the high-grade and fashionable style.

　　2.4 LX is equipped with a new DOHC inline four-cylinder engine and Honda’s famous i-VTEC (Intelligent Variable Valve Timing and Lift Electronic Control) system. The engine power reaches 180 HP and the torque reaches 225N·m, which is at the leading level in the 2.4L subdivision level. While achieving strong power, this car also maintains the consistent fuel-saving advantage of Honda products. The constant-speed fuel consumption of 90km/h is 6.5L/100km, which is the lowest in the same class, and the emission reaches the national IV standard.

　　The eighth generation Accord 2.4LX adopts a brand-new low center of gravity platform, and realizes a smooth chassis layout through a well-designed double wishbone front suspension and a new in-wheel multi-link rear suspension. The torsional stiffness of the car body is increased by 20% compared with the previous generation, and the stiffness of the suspension fulcrum is increased by 36%, giving people a stable and comfortable driving experience. Equipped with a new type of VGR steering system, which is generally only used in high-end cars, the vehicle has high directional stability at high speed, and good maneuverability and precision at low speed, which brings more driving pleasure.

　　In terms of safety technology and configuration, the eighth generation Accord 2.4 LX adopts Honda’s latest "Advanced Compatibility Design (ACE)" body structure technology, which improves the buffering effect of impact energy in various possible collision accidents. The amount of high-strength steel is also greatly increased, ensuring the firmness of the passenger compartment. The advanced energy-absorbing design of pedestrian protection head represents the future direction of automobile development.

　　The eighth generation Accord 2.4 LX is equipped with a complete six-in-one electronic security systems, including ABS anti-lock braking system, EBD electronic braking force distribution system, TCS traction control system, BA braking force auxiliary system, SC anti-skid system and VSA vehicle stability auxiliary system, which greatly improves the driving safety. Passive safety facilities include two-stage ignition front airbag, front seat side airbag, and active head restraint system that can reduce neck injury when the rear of the vehicle is collided, and cooperate with OPDS (occupant sitting posture perception) system to minimize the degree of injury when an accident occurs.

　　On April 20th, 2008, the first batch of C-NCAP crash test results of China Automotive Technology and Research Center in 2008 were released. The eighth generation Accord achieved the highest score of C-NCAP crash in the domestic car market with a total score of 50.3, becoming the only car that has won the super five-star evaluation so far. Experts from C-NCAP evaluated the safety performance of the Eighth Accord as "nearly perfect".

　　In terms of comfort and convenience, the eighth generation Accord 2.4 LX is equipped with electric sunroof, 4-direction adjustable electric folding exterior rearview mirror, SVC (Speed Sensing Sound Compensation System), cruise control system, dual-zone independent control automatic air conditioner and intelligent access system.

　　The listing of the eighth generation Accord 2.4LX makes the eighth generation Accord form four series of 2.4EXLNavi, 2.4EXNavi,2.4EX and 2.4LX at the 2.4L level, which is conducive to further consolidating its leading position in this market segment. At this point, the eighth generation Accord sedan has successively launched three gold displacement combinations of 2.0L, 2.4L and 3.5L, with a total of eight new models with different configurations, with accurate parking spaces in the price range of 181,800-339,800 yuan, thus building the most powerful product matrix in the medium-sized sedan market and providing consumers with the richest choices.

● Glorious coronation, the eighth generation Accord is "the strongest in history"

　　In 2008, affected by the aggravation of the US financial crisis and the slowdown of domestic macroeconomic growth, China’s automobile market has undergone considerable adjustment, and the medium-sized car market, which is regarded as the vane of the automobile market, bears the brunt. In the face of various unfavorable factors, the eighth generation Accord sedan went against the trend and became popular all the way, winning the annual sales champion of medium-sized cars with an impressive performance of 170,517 cars.

　　With the support and trust of customers and all walks of life, the eighth generation Accord was highly praised and affirmed in the annual model selection of major authoritative media at the end of 2008: Car Magazine’s 2009 car of the year, Strong Media Alliance, 2008 China Car Billboard, and so on. According to incomplete statistics, at present, the eighth generation Accord has won the annual model selection award issued by more than 30 authoritative media.

　

　　On January 6, 2008, when the eighth generation Accord sedan was officially launched, Guangzhou Honda said that the eighth generation Accord should set up four coordinates for the market: trend coordinates, technical coordinates, value coordinates and service coordinates. With the quality of leading peers, "B++" technology, "C-class" service comparable to imported luxury cars and the brand value brought by it, the eighth generation Accord sedan has not only been highly recognized by consumers, but also by the media and all walks of life. The sales volume of 170,000 vehicles, more than 30 annual model awards and the praise of countless consumers all prove the fact that the eighth generation Accord has become a veritable new coordinate in the medium-sized car market.

　　"There is no first in mind, only consistency", which is the long-term commitment of Accord brand to consumers. The person in charge of Guangzhou Honda said that sales volume and honor are only a result. In contrast, Guangzhou Honda pays more attention to the process of providing consumers with high-quality products and services. As long as we conscientiously implement the consumer-centered business philosophy and strive to do the best in every detail of products and services, no matter how the automobile market changes in 2009, the eighth generation Accord will continue to lead the trend of the medium-sized car market and climb the sales peak again!

　　Overview of parameter configuration table:

When young people buy a car, they often consider many factors. In addition to the high value, the configuration and control can not be less, and the price should be within their tolerance. What I bring to you today is a-. Let’s take a look at it together.

First of all, from the appearance, the front shape of Mercedes-Benz GLE coupe AMG looks very hard and simple. Coupled with the simple headlights, it is a bit more streamlined. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4944 mm * 2018 mm * 1716 mm. The car adopts simple lines, and the car body presents a personalized design style. With large-sized thick-walled tires, it looks full of movement. In the design of the rear end, the rear end looks very simple, and the taillights give people a very sharp feeling. Together with the unique exhaust pipe, the whole looks very avant-garde.

Sitting in the car, the interior looks very delicate and the overall visual effect is very distinctive. The steering wheel shape of the car is eye-catching, made of leather, and its practicality and face value are not bad. Let’s take a look at the central control, with the 12.3-inch touch-sensitive LCD central control screen, which makes the interior design quite layered and looks quite fashionable and concise. The dashboard and seats give people a good feeling, too. Let’s take a look. The dashboard of this car presents a concise design style, and the information is easy to read and clear. The car uses leather seats, equipped with functions such as electric adjustment with memory in the auxiliary seat, electric adjustment with memory in the seat, and seat proportion tilting, which makes it very comfortable to ride.

Equipped with car networking, driving mode selection, remote control key, rear wiper, interior atmosphere light and other configurations, it has rich functions and greatly improves its convenience of use.

After reading the above introduction, let’s make a summary. Many people buy SUVs because of their stronger passability. The car is practical and fully equipped, and it is a good helper for home travel.

date Shareholding amount Share of outstanding shares (%) Daily net purchase amount (RMB) Daily net trading volume (shares) Cumulative shareholding cost (yuan) 2024-3-18 1.14 million 3.90 4.023 million 112,000 28.46 2024-3-15 1.0279 million 3.52 114,900 3277 27.64 2024-3-14 1.0247 million 3.51 2.0247 million 57,000 27.62 2024-3-13 967,600 3.31 -5.3569 million -148,400 27.16 2024-3-12 1.1161 million 3.82 -2,014,900 -56,700 28.34 2024-3-11 1.1728 million 4.01 1.5913 million 45,100 28.69 2024-3-8 1,127,700 3.86 -4.5105 million -127,700 28.43 2024-3-7 1.2553 million 4.30 4.6507 million 129,300 29.13 2024-3-6 1,126,100 3.85 -10.721 million -285,800 yuan 28.34 2024-3-5 1.4119 million 4.83 -33.4948 million -878,200 30.20